Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H- quinazolin-4-ones

Please use this identifier to cite or link to this item: http://elar.urfu.ru/handle/10995/27469

Title:	Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H- quinazolin-4-ones
Authors:	Nosova, E. V. Lipunova, G. N. Slepukhin, P. A. Charushin, V. N.
Issue Date:	2013
Citation:	Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H- quinazolin-4-ones / E. V. Nosova, G. N. Lipunova, P. A. Slepukhin [et al.] // Journal of Fluorine Chemistry. — 2013. — Vol. 145. — P. 63-65.
Abstract:	A versatile pathway for the synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones from 4,5-difluoroanthranylic acid has been advanced. Nucleophilic amination-defluorination reaction of the 6,7-difluoro derivative of 3-amino-2-methyl-3H-quinazolin-4-one has been established to occur at position 7, as shown by X-ray crystallographic analysis. © 2012 Elsevier B.V.
Keywords:	3-AMINOQUINAZOLIN-4-ONES FLUORINE-CONTAINING QUINAZOLINONES NUCLEOPHILIC DISPLACEMENT REACTIONS X-RAY CRYSTALLOGRAPHY
URI:	http://elar.urfu.ru/handle/10995/27469
SCOPUS ID:	84871919265
WOS ID:	000315252900008
PURE ID:	900262
ISSN:	0022-1139
DOI:	10.1016/j.jfluchem.2012.10.003
Appears in Collections:	Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC

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