Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/27469
Title: Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H- quinazolin-4-ones
Authors: Nosova, E. V.
Lipunova, G. N.
Slepukhin, P. A.
Charushin, V. N.
Issue Date: 2013
Citation: Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H- quinazolin-4-ones / E. V. Nosova, G. N. Lipunova, P. A. Slepukhin [et al.] // Journal of Fluorine Chemistry. — 2013. — Vol. 145. — P. 63-65.
Abstract: A versatile pathway for the synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones from 4,5-difluoroanthranylic acid has been advanced. Nucleophilic amination-defluorination reaction of the 6,7-difluoro derivative of 3-amino-2-methyl-3H-quinazolin-4-one has been established to occur at position 7, as shown by X-ray crystallographic analysis. © 2012 Elsevier B.V.
Keywords: 3-AMINOQUINAZOLIN-4-ONES
FLUORINE-CONTAINING QUINAZOLINONES
NUCLEOPHILIC DISPLACEMENT REACTIONS
X-RAY CRYSTALLOGRAPHY
URI: http://hdl.handle.net/10995/27469
SCOPUS ID: 84871919265
WOS ID: 000315252900008
PURE ID: 900262
ISSN: 0022-1139
DOI: 10.1016/j.jfluchem.2012.10.003
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

Files in This Item:
File Description SizeFormat 
scopus-2013-0618.pdf212,02 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.