1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorRykunova, E. B.en
dc.contributor.authorMikeladze, M. A.en
dc.contributor.authorUtepova, I. A.en
dc.contributor.authorChupakhin, O. N.en
dc.contributor.authorGuzhova, I. V.en
dc.contributor.authorLazarev, V. F.en
dc.date.accessioned2024-04-05T16:34:26Z-
dc.date.available2024-04-05T16:34:26Z-
dc.date.issued2023-
dc.identifier.citationRykunova, EB, Mikeladze, MA, Utepova, IA, Chupakhin, ON, Guzhova, IV & Lazarev, VF 2023, 'Approbation of a New Model of Secondary Damage after Traumatic Brain Injury Based on Reprogrammed Rat Embryo Fibroblasts', Doklady Biochemistry and Biophysics, Том. 511, № 1, стр. 235-239. https://doi.org/10.1134/S1607672923700345harvard_pure
dc.identifier.citationRykunova, E. B., Mikeladze, M. A., Utepova, I. A., Chupakhin, O. N., Guzhova, I. V., & Lazarev, V. F. (2023). Approbation of a New Model of Secondary Damage after Traumatic Brain Injury Based on Reprogrammed Rat Embryo Fibroblasts. Doklady Biochemistry and Biophysics, 511(1), 235-239. https://doi.org/10.1134/S1607672923700345apa_pure
dc.identifier.issn1607-6729-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Hybrid Gold, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85174015731&doi=10.1134%2fS1607672923700345&partnerID=40&md5=63f8eb6dcbbf48077cd5ce88f51191c71
dc.identifier.otherhttps://link.springer.com/content/pdf/10.1134/S1607672923700345.pdfpdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/130854-
dc.description.abstractAbstract: The paper presents a new model of secondary injuries after traumatic brain injury. The model is based on the cultivation of rat embryonic fibroblasts reprogrammed to a neuronal phenotype in the presence of cerebrospinal fluid from injured rats. The presented model was used to test the therapeutic effect of inducers of the synthesis of chaperones from the classes of pyrrolylazines and indolylazines, which have neuroprotective properties. © 2023, The Author(s).en
dc.description.sponsorshipMinistry of Education and Science of the Russian Federation, Minobrnauka: 075-15-2021-683; Russian Science Foundation, RSF: 18-74-10087en
dc.description.sponsorshipThis work was supported by the Russian Science Foundation, project no. 18-74-10087.en
dc.description.sponsorshipRat embryonic fibroblasts DFK-3 were obtained from the Vertebrate Cell Culture Collection core facility, which was supported by a grant from the Ministry of Education and Science of the Russian Federation (agreement no. 075-15-2021-683). Cells were cultured in DMEM medium (BioloT, Russia) supplemented with 10% fetal bovine serum (Gibco, United States) and antibiotics penicillin 100 units/mL and streptomycin 0.1 mg/mL (BioloT, Russia) at 37°C and 5% CO. 2en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherPleiades Publishingen
dc.relationinfo:eu-repo/grantAgreement/RSF//18-74-10087en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceDoklady Biochemistry and Biophysics2
dc.sourceDoklady Biochemistry and Biophysicsen
dc.subjectCEREBROSPINAL FLUIDen
dc.subjectCHAPERONESen
dc.subjectHSP70en
dc.subjectPYRROLYLAZINE AND INDOLYLAZINE DERIVATIVESen
dc.subjectSECONDARY INJURIESen
dc.subjectTRAUMATIC BRAIN INJURYen
dc.subjectANIMALen
dc.subjectBRAIN INJURYen
dc.subjectCEREBROSPINAL FLUIDen
dc.subjectCOMPLICATIONen
dc.subjectNERVE CELLen
dc.subjectRATen
dc.subjectTRAUMATIC BRAIN INJURYen
dc.subjectANIMALSen
dc.subjectBRAIN INJURIESen
dc.subjectBRAIN INJURIES, TRAUMATICen
dc.subjectNEURONSen
dc.subjectRATSen
dc.titleApprobation of a New Model of Secondary Damage after Traumatic Brain Injury Based on Reprogrammed Rat Embryo Fibroblastsen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.type|info:eu-repo/semantics/publishedVersionen
dc.identifier.rsi63462359-
dc.identifier.doi10.1134/S1607672923700345-
dc.identifier.scopus85174015731-
local.contributor.employeeRykunova, E.B., Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federationen
local.contributor.employeeMikeladze, M.A., Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federationen
local.contributor.employeeUtepova, I.A., Ural Federal University, Yekaterinburg, Russian Federation, Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, Yekaterinburg, Russian Federationen
local.contributor.employeeChupakhin, O.N., Ural Federal University, Yekaterinburg, Russian Federation, Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, Yekaterinburg, Russian Federationen
local.contributor.employeeGuzhova, I.V., Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federationen
local.contributor.employeeLazarev, V.F., Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federationen
local.description.firstpage235-
local.description.lastpage239-
local.issue1-
local.volume511-
dc.identifier.wos001086576900015-
local.contributor.departmentInstitute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federationen
local.contributor.departmentUral Federal University, Yekaterinburg, Russian Federationen
local.contributor.departmentInstitute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, Yekaterinburg, Russian Federationen
local.identifier.pure46914084-
local.identifier.eid2-s2.0-85174015731-
local.fund.rsf18-74-10087-
local.identifier.wosWOS:001086576900015-
local.identifier.pmid37833611-
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