SYNTHESIS AND SPECTRAL CHARACTERIZATION OF 1,2,4- TRIAZOLE DERIVATIVES

Abstract

The azole derivatives are the prominent players in the pharmaceutical research as they possess several biological properties. In particular, triazoles represent a class of heterocyclic compounds with a wide variety of biological activities. Furthermore, heterocyclic compounds containing a 1,2,4-triazole nucleus have a broad spectrum of pharmacological activities, including anti-inflammatory, antimicrobial, anticancer, antiproliferative and apoptotic properties. Hence biological importance of heterocyclic compounds containing 1, 2, 4-triazole with their pharmacological potential has thereby made them extremely attractive research targets. Based on the above essential information, we have designed and synthesized different 1,2,4-triazole derivatives.