Mössbauer study of red blood cells from patients with erythremia

Abstract

Red blood cell samples from several patients with erythremia have been studied by Mössbauer spectroscopy. Quadrupole splitting and isomer shift for oxyhemoglobin from erythremic red blood cells and those of oxyhemoglobin from normal ones differ slightly, while these hyperfine parameters for deoxyhemoglobins are the same. An additional component in Mössbauer spectra of red blood cell samples was observed in some cases of erythremia. It is proposed that this component is related to ferritin-like iron and its content ranged from 13-15% to 5-7%. Mössbauer spectroscopy; Erythremia; Hemoglobin; Fe2+ electronic structure; Ferritin; (Normal adult red blood cell, Erythremic red blood cell). © 1989.