1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorKovalev, I. S.en
dc.contributor.authorZyryanov, G. V.en
dc.contributor.authorSantra, S.en
dc.contributor.authorMajee, A.en
dc.contributor.authorVaraksin, M. V.en
dc.contributor.authorCharushin, V. N.en
dc.date.accessioned2024-04-08T11:06:35Z-
dc.date.available2024-04-08T11:06:35Z-
dc.date.issued2022-
dc.identifier.citationKovalev, IS, Zyryanov, GV, Santra, S, Majee, A, Varaksin, MV & Charushin, VN 2022, 'Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities', Molecules, Том. 27, № 19, 6229. https://doi.org/10.3390/molecules27196229harvard_pure
dc.identifier.citationKovalev, I. S., Zyryanov, G. V., Santra, S., Majee, A., Varaksin, M. V., & Charushin, V. N. (2022). Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities. Molecules, 27(19), [6229]. https://doi.org/10.3390/molecules27196229apa_pure
dc.identifier.issn1420-3049-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access; Gold Open Access; Green Open Access3
dc.identifier.otherhttps://www.mdpi.com/1420-3049/27/19/6229/pdf?version=16638383381
dc.identifier.otherhttps://www.mdpi.com/1420-3049/27/19/6229/pdf?version=1663838338pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/131317-
dc.description.abstractAntimetabolites of folic acid represent a large group of drugs and drug candidates, including those for cancer chemotherapy. In this current review, the most common methods and approaches are presented for the synthesis of therapeutically significant antimetabolites of folic acid, which are Methotrexate (MTX), Raltitrexed (Tomudex, ZD1694), Pralatrexate, Pemetrexed, TNP-351, and Lometrexol. In addition, the applications or uses of these folic acid antimetabolites are also discussed. © 2022 by the authors.en
dc.description.sponsorshipMinistry of Science, ICT and Future Planning, MSIP, (075-15-2022-1118)en
dc.description.sponsorshipRussian Science Foundation, RSF, (20-43-01004)en
dc.description.sponsorshipThe analysis of synthetic approaches to antifolates was supported by the Russian Science Foundation (Project # 20-43-01004). The analysis of biological activity of antifolates was supported by the Ministry of Science and the Higher Education of RF (Ref. # 075-15-2022-1118, dated 29 June 2022).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.relationinfo:eu-repo/grantAgreement/RSF//20-43-01004en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceMolecules2
dc.sourceMoleculesen
dc.subjectANTIFOLATESen
dc.subjectAPPLICATIONSen
dc.subjectDRUGSen
dc.subjectFOLIC ACIDSen
dc.subjectSYNTHESISen
dc.titleFolic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunitiesen
dc.typeReviewen
dc.typeinfo:eu-repo/semantics/reviewen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/molecules27196229-
dc.identifier.scopus85139962002-
local.contributor.employeeKovalev I.S., Department of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeZyryanov G.V., Department of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federation, I. Ya. Postovskiy Institute of Organic Synthesis, Russian Academy of Sciences, Ural Branch, Yekaterinburg, 620219, Russian Federationen
local.contributor.employeeSantra S., Department of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeMajee A., Department of Chemistry, Visva-Bharati (A Central University), Santiniketan, 731235, Indiaen
local.contributor.employeeVaraksin M.V., Department of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federation, I. Ya. Postovskiy Institute of Organic Synthesis, Russian Academy of Sciences, Ural Branch, Yekaterinburg, 620219, Russian Federationen
local.contributor.employeeCharushin V.N., Department of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federation, I. Ya. Postovskiy Institute of Organic Synthesis, Russian Academy of Sciences, Ural Branch, Yekaterinburg, 620219, Russian Federationen
local.issue19-
local.volume27-
dc.identifier.wos000866947400001-
local.contributor.departmentDepartment of Organic & Biomolecular Chemistry, Ural Federal University, Yekaterinburg, 620002, Russian Federationen
local.contributor.departmentI. Ya. Postovskiy Institute of Organic Synthesis, Russian Academy of Sciences, Ural Branch, Yekaterinburg, 620219, Russian Federationen
local.contributor.departmentDepartment of Chemistry, Visva-Bharati (A Central University), Santiniketan, 731235, Indiaen
local.identifier.pure31022645-
local.identifier.pure14e5cbcd-17fa-4c3d-9fa4-cc0a4439055auuid
local.description.order6229-
local.identifier.eid2-s2.0-85139962002-
local.fund.rsf20-43-01004-
local.identifier.wosWOS:000866947400001-
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