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dc.contributor.authorSlovesnova, N. V.en
dc.contributor.authorPetrov, A. Y.en
dc.contributor.authorGlavatskih, S. А.en
dc.contributor.authorBolotova, А. V.en
dc.contributor.authorKopchuk, D. S.en
dc.date.accessioned2024-04-05T16:39:33Z-
dc.date.available2024-04-05T16:39:33Z-
dc.date.issued2023-
dc.identifier.citationSlovesnova, N, Petrov, A, Glavatskih, S, Bolotova, АV & Kopchuk, D 2023, 'The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract', International Journal of Drug Delivery Technology, Том. 13, № 04, стр. 1139-1144. https://doi.org/10.25258/ijddt.13.4.02harvard_pure
dc.identifier.citationSlovesnova, N., Petrov, A., Glavatskih, S., Bolotova, А. V., & Kopchuk, D. (2023). The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract. International Journal of Drug Delivery Technology, 13(04), 1139-1144. https://doi.org/10.25258/ijddt.13.4.02apa_pure
dc.identifier.issn0975-4415-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Bronze3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85185682800&doi=10.25258%2fijddt.13.4.02&partnerID=40&md5=d31173e87668e7ea7a55fc133970caa01
dc.identifier.otherhttps://doi.org/10.25258/ijddt.13.4.02pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/131162-
dc.description.abstractThe release rate of active pharmaceutical ingredients (APIs) from tablet dosage forms is significantly influenced by the composition of the formulation, in particular filler composition. In this work, we analyzed the impact of the ratio of excipients on the release rate of vinpocetine from a tablet containing Ginkgo biloba L. extract as the second API. Microcrystalline cellulose (MCC), hydroxypropylcellulose (L-HPC) mixed with MCC (up to 16% of HPC), and partially pregelatinized starch were used in different ratios as excipients. Moreover, tween-80 was used to study the effect of introduction of emulsifier on the APIs’ release rates. According to our findings, optimal APIs’ release rates are achieved when using the combination of MCC with HPC at a ratio of 2:3. © 2023, Dr. Yashwant Research Labs Pvt. Ltd.. All rights reserved.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherDr. Yashwant Research Labs Pvt. Ltd.en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceINTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY2
dc.sourceInternational Journal of Drug Delivery Technologyen
dc.subjectDISINTEGRATION TESTen
dc.subjectDISSOLUTION TESTen
dc.subjectGINKGO BILOBA L. EXTRACTen
dc.subjectVINPOCETINEen
dc.subjectCROSPOVIDONEen
dc.subjectEUDRAGITen
dc.subjectGINKGO BILOBA EXTRACTen
dc.subjectHYDROXYPROPYLCELLULOSEen
dc.subjectHYDROXYPROPYLMETHYLCELLULOSEen
dc.subjectMICROCRYSTALLINE CELLULOSEen
dc.subjectPOLYSORBATE 80en
dc.subjectSTARCHen
dc.subjectSULPIRIDEen
dc.subjectTERPENEen
dc.subjectVINPOCETINEen
dc.subjectANALYTICAL PARAMETERSen
dc.subjectANGLE OF REPOSEen
dc.subjectANIMAL EXPERIMENTen
dc.subjectANIMAL MODELen
dc.subjectANIMAL TISSUEen
dc.subjectARTICLEen
dc.subjectBIOAVAILABILITYen
dc.subjectBULK DENSITYen
dc.subjectCALIBRATIONen
dc.subjectCONTROLLED STUDYen
dc.subjectDISSOLUTIONen
dc.subjectDRUG DOSAGE FORMen
dc.subjectDRUG FORMULATIONen
dc.subjectDRUG GRANULATIONen
dc.subjectDRUG RELEASEen
dc.subjectDRUG SOLUBILITYen
dc.subjectEXCIPIENT COMPATIBILITYen
dc.subjectHAUSNER RATIOen
dc.subjectMALEen
dc.subjectMATHEMATICAL MODELen
dc.subjectNONHUMANen
dc.subjectPROGRESSION FREE SURVIVALen
dc.subjectSCANNING ELECTRON MICROSCOPYen
dc.subjectSURFACE PROPERTYen
dc.subjectTABLETen
dc.subjectTABLET COMPRESSIONen
dc.subjectTABLET DISINTEGRATIONen
dc.subjectTABLET DISINTEGRATION TIMEen
dc.subjectTABLET FRIABILITYen
dc.subjectTABLET HARDNESSen
dc.subjectTABLET THICKNESSen
dc.subjectTAPPED DENSITYen
dc.subjectTEMPERATUREen
dc.subjectTERAHERTZ SPECTROSCOPYen
dc.subjectVISCOSITYen
dc.subjectWETTABILITYen
dc.titleThe Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extracten
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.type|info:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.25258/ijddt.13.4.02-
dc.identifier.scopus85185682800-
local.contributor.employeeSlovesnova, N.V., Ural State Medical University, Yekaterinburg, Russian Federation, Ural Federal University, Chemical Engineering Institute, Yekaterinburg, Russian Federationen
local.contributor.employeePetrov, A.Y., Ural State Medical University, Yekaterinburg, Russian Federationen
local.contributor.employeeGlavatskih, S.А., I. Ya. Postovskiy Institute of Organic Synthesis, the Ural Division of the Russian Academy of Sciences, Russian Federationen
local.contributor.employeeBolotova, А.V., Ural State Medical University, Yekaterinburg, Russian Federationen
local.contributor.employeeKopchuk, D.S., Ural Federal University, Chemical Engineering Institute, Yekaterinburg, Russian Federationen
local.description.firstpage1139-
local.description.lastpage1144-
local.issue4-
local.volume13-
local.contributor.departmentUral State Medical University, Yekaterinburg, Russian Federationen
local.contributor.departmentUral Federal University, Chemical Engineering Institute, Yekaterinburg, Russian Federationen
local.contributor.departmentI. Ya. Postovskiy Institute of Organic Synthesis, the Ural Division of the Russian Academy of Sciences, Russian Federationen
local.identifier.pure53807061-
local.identifier.eid2-s2.0-85185682800-
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