ISSN: 2310-757X
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http://elar.urfu.ru/handle/10995/130596| Title: | Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones |
| Authors: | Steparuk, E. V. Obydennov, D. L. Sosnovskikh, V. Y. |
| Issue Date: | 2023 |
| Publisher: | MDPI |
| Citation: | Steparuk, EV, Obydennov, DL & Sosnovskikh, VY 2023, 'Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones', Molbank, Том. 2023, № 2, M1668. https://doi.org/10.3390/M1668 Steparuk, E. V., Obydennov, D. L., & Sosnovskikh, V. Y. (2023). Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones. Molbank, 2023(2), [M1668]. https://doi.org/10.3390/M1668 |
| Abstract: | A two-stage synthesis of 5-aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones (56–66% overall yields) was carried out by refluxing 5-aroyl-3-(benzyloxy)-2-(het)aryl-4H-pyran-4-ones with ammonium acetate in AcOH and subsequent debenzylation. The prepared N-unsubstituted 4-pyridones exist in the pyridone tautomeric form. © 2023 by the authors. |
| Keywords: | 3-HYDROXY-4-PYRIDONES 4-PYRONES CHELATING AGENTS DEBENZYLATION METALLOENZYME INHIBITORS TAUTOMERISM |
| URI: | http://elar.urfu.ru/handle/10995/130596 |
| Access: | info:eu-repo/semantics/openAccess cc-by |
| License text: | https://creativecommons.org/licenses/by/4.0/ |
| SCOPUS ID: | 85163774687 |
| WOS ID: | 001017254100001 |
| PURE ID: | 41528523 |
| ISSN: | 1422-8599 |
| DOI: | 10.3390/M1668 |
| Sponsorship: | Russian Science Foundation, RSF: 22-73-10236 This research was funded by the Russian Science Foundation, grant number 22-73-10236 (https://rscf.ru/project/22-73-10236/ (accessed on 24 April 2023)). |
| RSCF project card: | 22-73-10236 |
| Appears in Collections: | Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC |
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| 2-s2.0-85163774687.pdf | 604,12 kB | Adobe PDF | View/Open |
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