1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorDemin, A. M.en
dc.contributor.authorVakhrushev, A. V.en
dc.contributor.authorPershina, A. G.en
dc.contributor.authorValova, M. S.en
dc.contributor.authorEfimova, L. V.en
dc.contributor.authorSyomchina, A. A.en
dc.contributor.authorUimin, M. A.en
dc.contributor.authorMinin, A. S.en
dc.contributor.authorLevit, G. L.en
dc.contributor.authorKrasnov, V. P.en
dc.contributor.authorCharushin, V. N.en
dc.date.accessioned2022-10-19T05:21:21Z-
dc.date.available2022-10-19T05:21:21Z-
dc.date.issued2022-
dc.identifier.citationMagnetic-Responsive Doxorubicin-Containing Materials Based on Fe3O4 Nanoparticles with a SiO2/PEG Shell and Study of Their Effects on Cancer Cell Lines / A. M. Demin, A. V. Vakhrushev, A. G. Pershina et al. // International Journal of Molecular Sciences. — 2022. — Vol. 23. — Iss. 16. — 9093.en
dc.identifier.issn16616596-
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85136615931&doi=10.3390%2fijms23169093&partnerID=40&md5=ec7ab1d6d1e644d7325dd33395fb6796link
dc.identifier.urihttp://elar.urfu.ru/handle/10995/118059-
dc.description.abstractNovel nanocomposite materials based on Fe3O4 magnetic nanoparticles (MNPs) coated with silica and covalently modified by [(3-triethoxysilyl)propyl]succinic acid–polyethylene glycol (PEG 3000) conjugate, which provides a high level of doxorubicin (Dox) loading, were obtained. The efficiency of Dox desorption from the surface of nanomaterials under the action of an alternating magnetic field (AMF) in acidic and neutral media was evaluated. Their high cytotoxicity against tumor cells, as well as the drug release upon application of AMF, which leads to an increase in the cytotoxic effect, was demonstrated. © 2022 by the authors.en
dc.description.sponsorshipMinistry of Education and Science of the Russian Federation, Minobrnauka: 075-15-2020-777en
dc.description.sponsorshipThis research was funded by the Ministry of Science and Higher Education of the Russian Federation, grant number 075-15-2020-777.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceInternational Journal of Molecular Sciencesen
dc.subjectALTERNATING MAGNETIC FIELDen
dc.subjectDOXORUBICINen
dc.subjectDRUG-DELIVERYen
dc.subjectMAGNETIC NANOPARTICLESen
dc.subjectPEGen
dc.subjectSIO2en
dc.subjectTUMOR CELLSen
dc.subjectDOXORUBICINen
dc.subjectDRUG CARRIERen
dc.subjectMACROGOLen
dc.subjectMAGNETITE NANOPARTICLEen
dc.subjectNANOPARTICLEen
dc.subjectSILICON DIOXIDEen
dc.subjectCELL LINEen
dc.subjectHUMANen
dc.subjectMAGNETISMen
dc.subjectNEOPLASMen
dc.subjectPHen
dc.subjectCELL LINEen
dc.subjectDOXORUBICINen
dc.subjectDRUG CARRIERSen
dc.subjectHUMANSen
dc.subjectHYDROGEN-ION CONCENTRATIONen
dc.subjectMAGNETIC PHENOMENAen
dc.subjectMAGNETITE NANOPARTICLESen
dc.subjectNANOPARTICLESen
dc.subjectNEOPLASMSen
dc.subjectPOLYETHYLENE GLYCOLSen
dc.subjectSILICON DIOXIDEen
dc.titleMagnetic-Responsive Doxorubicin-Containing Materials Based on Fe3O4 Nanoparticles with a SiO2/PEG Shell and Study of Their Effects on Cancer Cell Linesen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/ijms23169093-
dc.identifier.scopus85136615931-
local.contributor.employeeDemin, A.M., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.employeeVakhrushev, A.V., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.employeePershina, A.G., Center of Bioscience and Bioengineering, Siberian State Medical University, Tomsk, 634050, Russian Federation, Research School of Chemistry & Applied Biomedical Sciences, National Research Tomsk Polytechnic University, Tomsk, 634050, Russian Federationen
local.contributor.employeeValova, M.S., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.employeeEfimova, L.V., Center of Bioscience and Bioengineering, Siberian State Medical University, Tomsk, 634050, Russian Federationen
local.contributor.employeeSyomchina, A.A., Biological Institute, National Research Tomsk State University, Tomsk, 634050, Russian Federationen
local.contributor.employeeUimin, M.A., Mikheev Institute of Metal Physics, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620990, Russian Federationen
local.contributor.employeeMinin, A.S., Mikheev Institute of Metal Physics, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620990, Russian Federationen
local.contributor.employeeLevit, G.L., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.employeeKrasnov, V.P., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.employeeCharushin, V.N., Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federation, Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, 620002, Russian Federationen
local.issue16-
local.volume23-
dc.identifier.wos000845657600001-
local.contributor.departmentPostovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620108, Russian Federationen
local.contributor.departmentCenter of Bioscience and Bioengineering, Siberian State Medical University, Tomsk, 634050, Russian Federationen
local.contributor.departmentResearch School of Chemistry & Applied Biomedical Sciences, National Research Tomsk Polytechnic University, Tomsk, 634050, Russian Federationen
local.contributor.departmentBiological Institute, National Research Tomsk State University, Tomsk, 634050, Russian Federationen
local.contributor.departmentMikheev Institute of Metal Physics, Russian Academy of Sciences (Ural Branch), Ekaterinburg, 620990, Russian Federationen
local.contributor.departmentInstitute of Chemical Engineering, Ural Federal University, Ekaterinburg, 620002, Russian Federationen
local.identifier.pure30850954-
local.description.order9093-
local.identifier.eid2-s2.0-85136615931-
local.identifier.wosWOS:000845657600001-
local.identifier.pmid36012356-
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