Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/111783
Title: Protective Effect of the Prunella Grandiflora L. Extract in Relation to the Toxic Effect of Etoposide Through the Example of Drosophila Melanogaster
Other Titles: Протекторный эффект экстракта Prunella grandiflora L. относительно токсического воздействия этопозида на примере Drosophila melanogaster
Authors: Antosyuk, O. N.
Bolotnik, E. V.
Postovalova, A. S.
Issue Date: 2021
Publisher: Siberian State Medical University
Siberian State Medical University
Citation: Antosyuk O. N. Protective Effect of the Prunella Grandiflora L. Extract in Relation to the Toxic Effect of Etoposide Through the Example of Drosophila Melanogaster [Протекторный эффект экстракта Prunella grandiflora L. относительно токсического воздействия этопозида на примере Drosophila melanogaster] / O. N. Antosyuk, E. V. Bolotnik, A. S. Postovalova. — DOI 10.3390/rel12070499 // Bulletin of Siberian Medicine. — 2021. — Vol. 20. — Iss. 2. — P. 7-11.
Abstract: The data on the protective properties of the Prunella grandiflora L. extract were obtained when used together with the anticancer drug etoposide on the experimental strain of Drosophila melanogaster. The combined use of etoposide and 10% extract of P. grandiflora decreased mortality in D. melanogaster individuals to 15% and doubled the average individual fertility compared to the use of this cytostatic drug without the extract. Using the SMART method, the presence of the antigenotoxic effect was identified, which manifests itself through the absence of chromosomal aberrations. © 2021 Siberian State Medical University. All rights reserved.
Keywords: ANTIGENOTOXIC EFFECT
DROSOPHILA MELANOGASTER
ETOPOSIDE
MEDICINAL PLANTS
PROTECTIVE PROPERTIES
SMART
URI: http://hdl.handle.net/10995/111783
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85111717811
PURE ID: 22844687
ISSN: 1682-0363
DOI: 10.3390/rel12070499
metadata.dc.description.sponsorship: Source of financing. This work was supported by the Government of the Russian Federation (Decree No. 211, contract No 02.A03.21.0006).
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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