Protective Effect of the Prunella Grandiflora L. Extract in Relation to the Toxic Effect of Etoposide Through the Example of Drosophila Melanogaster

Antosyuk, O. N.; Bolotnik, E. V.; Postovalova, A. S.

doi:10.20538/1682-0363-2021-2-6-11

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Поле DC	Значение	Язык
dc.contributor.author	Antosyuk, O. N.	en
dc.contributor.author	Bolotnik, E. V.	en
dc.contributor.author	Postovalova, A. S.	en
dc.date.accessioned	2022-05-12T08:22:50Z	-
dc.date.available	2022-05-12T08:22:50Z	-
dc.date.issued	2021	-
dc.identifier.citation	Antosyuk O. N. Protective Effect of the Prunella Grandiflora L. Extract in Relation to the Toxic Effect of Etoposide Through the Example of Drosophila Melanogaster [Протекторный эффект экстракта Prunella grandiflora L. относительно токсического воздействия этопозида на примере Drosophila melanogaster] / O. N. Antosyuk, E. V. Bolotnik, A. S. Postovalova. — DOI 10.3390/rel12070499 // Bulletin of Siberian Medicine. — 2021. — Vol. 20. — Iss. 2. — P. 7-11.	en
dc.identifier.issn	1682-0363	-
dc.identifier.other	All Open Access, Gold	3
dc.identifier.uri	http://elar.urfu.ru/handle/10995/111783	-
dc.description.abstract	The data on the protective properties of the Prunella grandiflora L. extract were obtained when used together with the anticancer drug etoposide on the experimental strain of Drosophila melanogaster. The combined use of etoposide and 10% extract of P. grandiflora decreased mortality in D. melanogaster individuals to 15% and doubled the average individual fertility compared to the use of this cytostatic drug without the extract. Using the SMART method, the presence of the antigenotoxic effect was identified, which manifests itself through the absence of chromosomal aberrations. © 2021 Siberian State Medical University. All rights reserved.	en
dc.description.sponsorship	Source of financing. This work was supported by the Government of the Russian Federation (Decree No. 211, contract No 02.A03.21.0006).	en
dc.format.mimetype	application/pdf	en
dc.language.iso	en	en
dc.publisher	Siberian State Medical University	en1
dc.publisher	Siberian State Medical University	en
dc.rights	info:eu-repo/semantics/openAccess	en
dc.source	Bull. Sib. Med.	2
dc.source	Bulletin of Siberian Medicine	en
dc.subject	ANTIGENOTOXIC EFFECT	en
dc.subject	DROSOPHILA MELANOGASTER	en
dc.subject	ETOPOSIDE	en
dc.subject	MEDICINAL PLANTS	en
dc.subject	PROTECTIVE PROPERTIES	en
dc.subject	SMART	en
dc.title	Protective Effect of the Prunella Grandiflora L. Extract in Relation to the Toxic Effect of Etoposide Through the Example of Drosophila Melanogaster	en
dc.title.alternative	Протекторный эффект экстракта Prunella grandiflora L. относительно токсического воздействия этопозида на примере Drosophila melanogaster	ru
dc.type	Article	en
dc.type	info:eu-repo/semantics/article	en
dc.type	info:eu-repo/semantics/publishedVersion	en
dc.identifier.rsi	46317623	-
dc.identifier.doi	10.20538/1682-0363-2021-2-6-11	-
dc.identifier.scopus	85111717811	-
local.contributor.employee	Antosyuk Olga, N., Department of Biodiversity and Bioecology, Institute of Natural Sciences and Mathematics, Ural Federal University (UrFU) named after the first President of Russia B.N. Yeltsin, 19, Mira Str., Yekaterinburg, 620002, Russian Federation; Bolotnik Elizaveta, V., Laboratory for the Introduction of Herbaceous Plants, Botanical Garden of the Ural Branch, The Russian Academy of Sciences, 202а, 8 March Str., Yekaterinburg, 620144, Russian Federation; Postovalova Alisa, S., Department of Biodiversity and Bioecology, Institute of Natural Sciences and Mathematics, Ural Federal University (UrFU) named after the first President of Russia B.N. Yeltsin, 19, Mira Str., Yekaterinburg, 620002, Russian Federation	en
local.description.firstpage	7	-
local.description.lastpage	11	-
local.issue	2	-
local.volume	20	-
dc.identifier.wos	000674629200001	-
local.contributor.department	Department of Biodiversity and Bioecology, Institute of Natural Sciences and Mathematics, Ural Federal University (UrFU) named after the first President of Russia B.N. Yeltsin, 19, Mira Str., Yekaterinburg, 620002, Russian Federation; Laboratory for the Introduction of Herbaceous Plants, Botanical Garden of the Ural Branch, The Russian Academy of Sciences, 202а, 8 March Str., Yekaterinburg, 620144, Russian Federation	en
local.identifier.pure	22844687	-
local.identifier.eid	2-s2.0-85111717811	-
local.identifier.wos	WOS:000674629200001	-
Располагается в коллекциях:	Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC

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