Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/103319
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dc.contributor.authorAkram, N. M. D.en
dc.contributor.authorGopal, N. M.en
dc.contributor.authorBalakrishna, A.en
dc.contributor.authorReddy, N. B.en
dc.date.accessioned2021-08-31T15:08:57Z-
dc.date.available2021-08-31T15:08:57Z-
dc.date.issued2020-
dc.identifier.citationMethod development and validation of a reversed phase HPLC method for determination of Anastrazole and Temozolomide in pharmaceutical dosage form / N. M. D. Akram, N. M. Gopal, A. Balakrishna, et al. — DOI 10.1063/5.0018206 // AIP Conference Proceedings. — 2020. — Vol. 2280. — 0018206.en
dc.identifier.isbn9780735440104-
dc.identifier.issn0094243X-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Bronze, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85096433367&doi=10.1063%2f5.0018206&partnerID=40&md5=0f0a24b2b736b78f7b2a1bc263654a6a
dc.identifier.otherhttps://elar.urfu.ru/bitstream/10995/81124/1/978-5-6044427-0-8_2019_085.pdfm
dc.identifier.urihttp://hdl.handle.net/10995/103319-
dc.description.abstractA new simple assay method has been developed and validated for the determination of Anastrazole and Temozolomide using reverse-phase high-performance liquid chromatography in their pharmaceutical dosage form. The chromatographic separation was performed on an Inertsil ODS (4.6 x 150mm, 5m) using mobile phase phosphate buffer pH 3.0 and methanol of 30:70% v/v at a flow rate of 0.8mL/min. Analytes were detected at 260nm. The method was found to be linear in the concentration range of 1-5μg/mL for both medicaments with the coefficient value (R2) of >0.999. The accuracy was measured via recovery studies and found to be acceptable and the percentage recoveries were found in the range of 98.81-100.720 and 99.290-100.700%. The proposed method was successfully validated and applied for the quantitative estimation of these drugs in both bulk and tablet dosage forms. © 2020 Author(s).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherAmerican Institute of Physics Inc.en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceAIP Conf. Proc.2
dc.sourceAIP Conference Proceedingsen
dc.titleMethod development and validation of a reversed phase HPLC method for determination of Anastrazole and Temozolomide in pharmaceutical dosage formen
dc.typeConference Paperen
dc.typeinfo:eu-repo/semantics/conferenceObjecten
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1063/5.0018206-
dc.identifier.scopus85096433367-
local.contributor.employeeAkram, N.M.D., Santhiram Engineering College, Nandyal, Kurnool (Dt), Andhra Pradesh, India
local.contributor.employeeGopal, N.M., Santhiram College of Pharmacy, Nandyal, Kurnool(Dt), Andhra Pradesh, India
local.contributor.employeeBalakrishna, A., Rajeev Gandhi Memorial College of Engineering and Technology (Autonomous), Nandyal, Andhra Pradesh, 518501, India
local.contributor.employeeReddy, N.B., Ural Federal University, Chemical Engineering Institute, Yekaterinburg, 620002, Russian Federation
local.volume2280-
local.contributor.departmentSanthiram Engineering College, Nandyal, Kurnool (Dt), Andhra Pradesh, India
local.contributor.departmentSanthiram College of Pharmacy, Nandyal, Kurnool(Dt), Andhra Pradesh, India
local.contributor.departmentRajeev Gandhi Memorial College of Engineering and Technology (Autonomous), Nandyal, Andhra Pradesh, 518501, India
local.contributor.departmentUral Federal University, Chemical Engineering Institute, Yekaterinburg, 620002, Russian Federation
local.identifier.pure20138157-
local.identifier.purea207b225-ece8-4b11-92f8-a930e5bd908auuid
local.description.order0018206-
local.identifier.eid2-s2.0-85096433367-
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