Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/102696
Title: Kinetic Resolution of Racemic 2-Aryloxy Propionyl Chlorides Using Enantiopure (S)-3,4-Dihydro-3-methyl-2H-[1,4]benzoxazines
Authors: Vakarov, S. A.
Chulakov, E. N.
Sadretdinova, L. S.
Kodess, M. I.
Ezhikova, M. A.
Pervova, M. G.
Ganebnykh, I. N.
Levit, G. L.
Krasnov, V. P.
Issue Date: 2020
Publisher: Wiley-Blackwell
Citation: Kinetic Resolution of Racemic 2-Aryloxy Propionyl Chlorides Using Enantiopure (S)-3,4-Dihydro-3-methyl-2H-[1,4]benzoxazines / S. A. Vakarov, E. N. Chulakov, L. S. Sadretdinova, et al. — DOI 10.1002/slct.202000629 // ChemistrySelect. — 2020. — Vol. 5. — Iss. 13. — P. 4069-4073.
Abstract: Stereoselectivity in the mutual kinetic resolution (KR) of racemic 3,4-dihydro-3-methyl-2H-[1,4]benzoxazines and racemic 2-aryloxy propionyl chlorides was studied. Based on the results obtained, preparative methods for single enantiomers of a series of 2-aryloxy propionic acids via acylative KR of their racemates with enantiopure (S)-3,4-dihydro-3-methyl-2H-[1,4]benzoxazines have been proposed. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords: ACYL CHLORIDES
ACYLATION
BENZOXAZINES
KINETIC RESOLUTION
STEREOSELECTIVITY
URI: http://hdl.handle.net/10995/102696
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85084705676
PURE ID: 12670812
ISSN: 23656549
DOI: 10.1002/slct.202000629
metadata.dc.description.sponsorship: The work was financially supported by the Russian Science Foundation (grant 19‐13‐00231, in the part of studying mutual kinetic resolution) and the Russian Foundation for Basic Research (grant 18‐33‐00027_mol_a, in the part of preparation of enantiomers of 2‐aryloxy propionic acids). Analytical studies were carried out using equipment of the Centre for Joint Use “Spectroscopy and Analysis of Organic Compounds” at the Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch)
RSCF project card: 19-13-00231
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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