Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/101897
Title: Microwave-Assisted Synthesis of N-Substituted Maleimide Derivatives as Exogenous Antioxidant Agents
Authors: Rammohan, A.
Mallikarjuna Reddy, G.
Raul, Garcia, J.
Zyryanov, G. V.
Sravya, G.
Bakthavatchala Reddy, N.
Yuvaraja, G.
Зырянов, Г. В.
Issue Date: 2019
Publisher: HeteroCorporation
Citation: Microwave-Assisted Synthesis of N-Substituted Maleimide Derivatives as Exogenous Antioxidant Agents / A. Rammohan, G. Mallikarjuna Reddy, J. Raul Garcia, et al. — DOI 10.1002/jhet.3421 // Journal of Heterocyclic Chemistry. — 2019. — Vol. 56. — Iss. 2. — P. 470-476.
Abstract: A series of N-substituted maleimide derivatives have been developed via acetic acid-mediated microwave reaction pathway, which was identified as the incomparable method for this maleimide compounds. All the synthesized compounds were tested for antioxidant activity by DPPH and H 2 O 2 methods. Compounds 5h and 5m were displayed with higher antioxidant activity in two methods. The structure–activity relationship demonstrated that the compounds having electron releasing substitutions 5h and 5m generally show beneficial activity than electron capture substitution cores. Thus, compounds 5h and 5m may be useful as an exogenous antioxidant. © 2018 Wiley Periodicals, Inc.
Keywords: 1 [4 (BENZYLIDENEAMINO)PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(2 AMINOBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(2 BROMOBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(2 FLUOROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(2 IODOBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(3 CHLOROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 BROMOBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 CHLOROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 FLUOROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 HYDROXYBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 IODOBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 METHOXYBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 METHYLBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 NITROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1 [4 [(4 TRIFLUOROBENZYLIDENE)AMINO]PHENYL] 1H PYRROLE 2,5 DIONE
1,1 DIPHENYL 2 PICRYLHYDRAZYL
ACETIC ACID
ASCORBIC ACID
HYDROGEN PEROXIDE
MALEIMIDE DERIVATIVE
ANTIOXIDANT ACTIVITY
CONTROLLED STUDY
DRUG MECHANISM
DRUG SYNTHESIS
IN VITRO STUDY
MICROWAVE ASSISTED SYNTHESIS
STRUCTURE ACTIVITY RELATION
SUBSTITUTION REACTION
SYNTHESIS
URI: http://hdl.handle.net/10995/101897
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85057838110
PURE ID: 9055456
4b20a18f-9795-4954-a2ee-08d58d18d5f3
ISSN: 0022152X
DOI: 10.1002/jhet.3421
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

Files in This Item:
File Description SizeFormat 
2-s2.0-85057838110.pdf100,88 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.