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dc.contributor.authorde, Abreu, M. S.en
dc.contributor.authorGenario, R.en
dc.contributor.authorGiacomini, A. C. V. V.en
dc.contributor.authorDemin, K. A.en
dc.contributor.authorLakstygal, A. M.en
dc.contributor.authorAmstislavskaya, T. G.en
dc.contributor.authorFontana, B. D.en
dc.contributor.authorParker, M. O.en
dc.contributor.authorKalueff, A. V.en
dc.date.accessioned2021-08-31T14:58:40Z-
dc.date.available2021-08-31T14:58:40Z-
dc.date.issued2020-
dc.identifier.citationZebrafish as a Model of Neurodevelopmental Disorders / M. S. de Abreu, R. Genario, A. C. V. V. Giacomini, et al. — DOI 10.1016/j.neuroscience.2019.08.034 // Neuroscience. — 2020. — Vol. 445. — P. 3-11.en
dc.identifier.issn3064522-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85075860800&doi=10.1016%2fj.neuroscience.2019.08.034&partnerID=40&md5=2566d85cad387f16742f7dfe46d56ca3
dc.identifier.otherhttps://researchportal.port.ac.uk/portal/files/15367039/Zebrafish_as_a_Model_of_Neurodevelopmental_Disorders.pdfm
dc.identifier.urihttp://elar.urfu.ru/handle/10995/101653-
dc.description.abstractNeurodevelopmental disorders (NDDs) caused by aberrant brain growth and development are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are a valuable tool for studying NDD pathobiology and therapies. Mounting evidence suggests the zebrafish (Danio rerio) as a useful model organism to study NDDs, possessing both high physiological homology to humans and sensitivity to pharmacological and genetic manipulations. Here, we summarize experimental models of NDDs in zebrafish and highlight the growing translational significance of zebrafish NDD-related phenotypes. We also emphasize the need in further development of zebrafish models of NDDs to improve our understanding of their pathogenesis and therapeutic treatments. © 2019 IBROen
dc.description.sponsorshipThis research is supported by the Russian Science Foundation grant 19-05-00053. KAD is supported by the Russian Foundation for Basic Research grant 18‐34‐00996, the President of Russia PhD Fellowship and the SPSU Rector's Productivity Fellowship for PhD students. ACVVG is supported by the Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS) research fellowships 17/2551-0001-269-0. AVK is the President of the International Stress and Behavior Society (ISBS, www.stress-and-behavior .com) and the Chair of the International Zebrafish Neuroscience Research Consortium (ZNRC) that coordinated this multi-laboratory collaborative project.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherElsevier Ltden
dc.relationinfo:eu-repo/grantAgreement/RSF//19-05-00053en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceNeuroscience2
dc.sourceNeuroscienceen
dc.subjectANIMAL MODELSen
dc.subjectATTENTION-DEFICIT/HYPERACTIVITY DISORDERen
dc.subjectAUTISMen
dc.subjectGENETIC MODELSen
dc.subjectNEURODEVELOPMENTen
dc.subjectVALPROIC ACIDen
dc.subjectATTENTION DEFICIT DISORDERen
dc.subjectBEHAVIOR DISORDERen
dc.subjectDISEASE MODELen
dc.subjectENVIRONMENTAL EXPOSUREen
dc.subjectENVIRONMENTAL FACTORen
dc.subjectGENE IDENTIFICATIONen
dc.subjectGENE MUTATIONen
dc.subjectGENETIC RISKen
dc.subjectHUMANen
dc.subjectMENTAL DISEASEen
dc.subjectMICROCEPHALYen
dc.subjectNONHUMANen
dc.subjectPATHOGENESISen
dc.subjectPHENOTYPEen
dc.subjectPRENATAL EXPOSUREen
dc.subjectPRIORITY JOURNALen
dc.subjectREVIEWen
dc.subjectSCHIZOPHRENIAen
dc.subjectSIGNAL TRANSDUCTIONen
dc.subjectZEBRA FISHen
dc.subjectANIMALen
dc.subjectANIMAL MODELen
dc.subjectBRAINen
dc.subjectDISEASE MODELen
dc.subjectQUALITY OF LIFEen
dc.subjectANIMALSen
dc.subjectBRAINen
dc.subjectDISEASE MODELS, ANIMALen
dc.subjectHUMANSen
dc.subjectMODELS, ANIMALen
dc.subjectNEURODEVELOPMENTAL DISORDERSen
dc.subjectQUALITY OF LIFEen
dc.subjectZEBRAFISHen
dc.titleZebrafish as a Model of Neurodevelopmental Disordersen
dc.typeReviewen
dc.typeinfo:eu-repo/semantics/reviewen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1016/j.neuroscience.2019.08.034-
dc.identifier.scopus85075860800-
local.contributor.employeede Abreu, M.S., Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil, The International Zebrafish Neuroscience Research Consortium (ZNRC), SlidellLA, United States
local.contributor.employeeGenario, R., Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil
local.contributor.employeeGiacomini, A.C.V.V., Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil, Postgraduate Program in Environmental Sciences, University of Passo Fundo, Passo Fundo, Brazil
local.contributor.employeeDemin, K.A., Institute of Experimental Medicine, Almazov National Medical Research Center, Ministry of Healthcare of Russian Federation, St. Petersburg, Russian Federation, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russian Federation
local.contributor.employeeLakstygal, A.M., Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russian Federation, Granov Russian Scientific Research Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, Pesochny, Russian Federation
local.contributor.employeeAmstislavskaya, T.G., Research Institute of Physiology and Basic Medicine, Novosibirsk, Russian Federation
local.contributor.employeeFontana, B.D., Brain and Behaviour Laboratory, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, United Kingdom
local.contributor.employeeParker, M.O., Brain and Behaviour Laboratory, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, United Kingdom
local.contributor.employeeKalueff, A.V., School of Pharmacy, Southwest University, Chongqing, China, Ural Federal University, Ekaterinburg, Russian Federation
local.description.firstpage3-
local.description.lastpage11-
local.volume445-
dc.identifier.wos000573888400002-
local.contributor.departmentBioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil
local.contributor.departmentThe International Zebrafish Neuroscience Research Consortium (ZNRC), SlidellLA, United States
local.contributor.departmentPostgraduate Program in Environmental Sciences, University of Passo Fundo, Passo Fundo, Brazil
local.contributor.departmentInstitute of Experimental Medicine, Almazov National Medical Research Center, Ministry of Healthcare of Russian Federation, St. Petersburg, Russian Federation
local.contributor.departmentInstitute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russian Federation
local.contributor.departmentGranov Russian Scientific Research Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, Pesochny, Russian Federation
local.contributor.departmentResearch Institute of Physiology and Basic Medicine, Novosibirsk, Russian Federation
local.contributor.departmentBrain and Behaviour Laboratory, School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, United Kingdom
local.contributor.departmentSchool of Pharmacy, Southwest University, Chongqing, China
local.contributor.departmentUral Federal University, Ekaterinburg, Russian Federation
local.identifier.pure326464cf-9729-4c20-b3bc-724dc6d83c98uuid
local.identifier.pure13909898-
local.identifier.eid2-s2.0-85075860800-
local.fund.rsf19-05-00053-
local.fund.rffi18-34-00996-
local.identifier.wosWOS:000573888400002-
local.identifier.pmid31472215-
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