SYNTHESIS OF A NEW CLASS OF PYRAZOLYL-1,2,4-TRIAZOLE AMINE DERIVATIVES

Abstract

Pyrazole, which is a five-membered heterocyclic ring containing two adjacent nitrogen, can be found in many industrial fields. Pyrazole and its derivatives show a variety of pharmaceutical activities such as anti-inflammatory, and antioxidant, antimicrobial, analgesic, and antipyretic activities. On the other hand 1,2,4-triazole nucleus have a broad spectrum of pharmacological activities, including anti-inflammatory, antimicrobial anticancer, antiproliferative and apoptotic properties. Based on the above information, we have been planned to synthesize different pyrazolyl-1,2,4-triazole derivatives.