1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorSutunkova, M. P.en
dc.contributor.authorSolovyeva, S. N.en
dc.contributor.authorChernyshov, I. N.en
dc.contributor.authorKlinova, S. V.en
dc.contributor.authorGurvich, V. B.en
dc.contributor.authorShur, V. Y.en
dc.contributor.authorShishkina, E. V.en
dc.contributor.authorZubarev, I. V.en
dc.contributor.authorPrivalova, L. I.en
dc.contributor.authorKatsnelson, B. A.en
dc.contributor.authorШур, В. Я.ru
dc.date.accessioned2020-09-29T09:47:24Z-
dc.date.available2020-09-29T09:47:24Z-
dc.date.issued2020-
dc.identifier.citationManifestation of systemic toxicity in rats after a short-time inhalation of lead oxide nanoparticles / M. P. Sutunkova, S. N. Solovyeva, I. N. Chernyshov, S. V. Klinova, et al. . — DOI 10.3390/ijms21030690 // International Journal of Molecular Sciences. — 2020. — Vol. 3. — Iss. 21. — 690.en
dc.identifier.issn1661-6596-
dc.identifier.otherhttps://www.mdpi.com/1422-0067/21/3/690/pdfpdf
dc.identifier.other1good_DOI
dc.identifier.otherec31671f-24cf-4e32-8f7d-8111995ea96cpure_uuid
dc.identifier.otherhttp://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85078263640m
dc.identifier.urihttp://elar.urfu.ru/handle/10995/90450-
dc.description.abstractOutbred female rats were exposed to inhalation of lead oxide nanoparticle aerosol produced right then and there at a concentration of 1.30 ± 0.10 mg/m3 during 5 days for 4 h a day in a nose-only setup. A control group of rats were sham-exposed in parallel under similar conditions. Even this short-time exposure of a relatively low level was associated with nanoparticles retention demonstrable by transmission electron microscopy in the lungs and the olfactory brain. Some impairments were found in the organism’s status in the exposed group, some of which might be considered lead-specific toxicological outcomes (in particular, increase in reticulocytes proportion, in δ-aminolevulinic acid (δ-ALA) urine excretion, and the arterial hypertension’s development). © 2020 by the authors. Licensee MDPI, Basel, Switzerland.en
dc.description.sponsorshipFunding: This work was funded by the budget of the Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPI AGen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.sourceInternational Journal of Molecular Sciencesen
dc.subjectINHALATION EXPOSUREen
dc.subjectLEAD OXIDEen
dc.subjectNANOPARTICLESen
dc.subjectTOXICITYen
dc.subjectALBUMINen
dc.subjectALKALINE PHOSPHATASEen
dc.subjectAMYLASEen
dc.subjectASPARTATE AMINOTRANSFERASEen
dc.subjectBRAIN NATRIURETIC PEPTIDEen
dc.subjectCATALASEen
dc.subjectCERULOPLASMINen
dc.subjectCOPROPORPHYRINen
dc.subjectCREATININEen
dc.subjectENDOTHELIN 1en
dc.subjectGAMMA GLUTAMYLTRANSFERASEen
dc.subjectGLOBULINen
dc.subjectGLUCOSEen
dc.subjectGLUTATHIONEen
dc.subjectHEMOGLOBINen
dc.subjectLACTATE DEHYDROGENASEen
dc.subjectLEAD OXIDE NANOPARTICLEen
dc.subjectMALONALDEHYDEen
dc.subjectMETAL NANOPARTICLEen
dc.subjectMYOGLOBINen
dc.subjectPROTEINen
dc.subjectTROPONINen
dc.subjectUNCLASSIFIED DRUGen
dc.subjectUREAen
dc.subjectURIC ACIDen
dc.subjectVASCULOTROPINen
dc.subjectANIMAL EXPERIMENTen
dc.subjectANIMAL MODELen
dc.subjectANIMAL TISSUEen
dc.subjectARTICLEen
dc.subjectBLOOD FLOWen
dc.subjectBODY MASSen
dc.subjectBRAIN MASSen
dc.subjectBRONCHOALVEOLAR LAVAGE FLUIDen
dc.subjectCELL COUNTen
dc.subjectCONTROLLED STUDYen
dc.subjectDIASTOLIC BLOOD PRESSUREen
dc.subjectDNA FRAGMENTATIONen
dc.subjectELECTROCARDIOGRAPHYen
dc.subjectERYTHROCYTE COUNTen
dc.subjectEXPOSUREen
dc.subjectFEMALEen
dc.subjectHEART MASSen
dc.subjectHEART RATEen
dc.subjectHEMATOCRITen
dc.subjectHYPERTENSIONen
dc.subjectLEAD POISONINGen
dc.subjectLIVER MASSen
dc.subjectLUNG MASSen
dc.subjectMEAN CORPUSCULAR HEMOGLOBINen
dc.subjectMEAN CORPUSCULAR VOLUMEen
dc.subjectMEAN PLATELET VOLUMEen
dc.subjectNEUTROPHILen
dc.subjectNONHUMANen
dc.subjectPARTICLE SIZEen
dc.subjectRATen
dc.subjectSCANNING ELECTRON MICROSCOPYen
dc.subjectSPLEEN SIZEen
dc.subjectSYSTOLIC BLOOD PRESSUREen
dc.subjectTOXICITYen
dc.subjectTRANSMISSION ELECTRON MICROSCOPYen
dc.subjectURINARY EXCRETIONen
dc.titleManifestation of systemic toxicity in rats after a short-time inhalation of lead oxide nanoparticlesen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/ijms21030690-
dc.identifier.scopus85078263640-
local.affiliationThe Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationen
local.affiliationThe Institute of Natural Sciences, Ural Federal University, Ekaterinburg, 620000, Russian Federationen
local.contributor.employeeSutunkova, M.P., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeSolovyeva, S.N., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeChernyshov, I.N., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeKlinova, S.V., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeGurvich, V.B., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeShur, V.Y., The Institute of Natural Sciences, Ural Federal University, Ekaterinburg, 620000, Russian Federationru
local.contributor.employeeShishkina, E.V., The Institute of Natural Sciences, Ural Federal University, Ekaterinburg, 620000, Russian Federationru
local.contributor.employeeZubarev, I.V., The Institute of Natural Sciences, Ural Federal University, Ekaterinburg, 620000, Russian Federationru
local.contributor.employeePrivalova, L.I., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.contributor.employeeKatsnelson, B.A., The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Str, Ekaterinburg, 620014, Russian Federationru
local.issue21-
local.volume3-
dc.identifier.wos000522551600004-
local.identifier.pure11996370-
local.description.order690-
local.identifier.eid2-s2.0-85078263640-
local.identifier.wosWOS:000522551600004-
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