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|Title:||K2CO3/Al2O3: An efficient and recyclable catalyst for one-pot, three components synthesis of α-aminophosphonates and bioactivity evaluation|
Zyryanov, G. V.
Reddy, N. B.
Зырянов, Г. В.
|Publisher:||Chemical Publishing Co.|
|Citation:||K2CO3/Al2O3: An efficient and recyclable catalyst for one-pot, three components synthesis of α-aminophosphonates and bioactivity evaluation / G. Sravya, G. Suresh, G. V. Zyryanov, A. Balakrishna, et al. . — DOI 10.14233/ajchem.2019.22194 // Asian Journal of Chemistry. — 2019. — Vol. 10. — Iss. 31. — P. 2383-2388.|
|Abstract:||A simple and efficient method has been employed for synthesis of a novel series of biologically active α-aminophosphonates (4a-j) by reacting 1H-benzo[d]imidazole-2-carbaldehyde (1) and various aromatic amines (2a-j) and diethyl/dimethyl phosphite (3) by Kabachnik-Field's reaction in the presence of efficient heterogeneous K2CO3/Al2O3 catalyst under solvent-free conditions at 140 ºC. Structures of all the compounds were confirmed by 1H, 13C and 31P NMR and LC-MS. In addition to this antioxidant activity were also evaluated. © 2019 Chemical Publishing Co.. All rights reserved.|
|Appears in Collections:||Научные публикации, проиндексированные в SCOPUS и WoS CC|
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