Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/61843
Title: Effect of Alkylation on the Kinetic Stability of Arsenodiester and Organoarsenicals against Hydrolysis: A Theoretical Study
Authors: Boota Singh
Rohan Ranjan Waliya
Santra, Sougata
Zyryanov, G. V.
Kousik Giri
Зырянов, Г. В.
Issue Date: 2018
Publisher: Уральский федеральный университет
Citation: Effect of Alkylation on the Kinetic Stability of Arsenodiester and Organoarsenicals against Hydrolysis: A Theoretical Study / Boota Singh, Rohan Ranjan Waliya, Sougata Santra, G. V. Zyryanov, Kousik Giri // Chimica Techno Acta. — 2018. — Vol. 5, No. 2. — P. 96-103.
Abstract: Arsenic diesters have same structural and chemical properties as Pi (phosphate) diester. Beside this structural similarity, arsenate is not considered by cellular processes to replace phosphate. Quantum calculation reveals that this happens due to very high hydrolysis rate of Asi diester (As–O-bond-based compounds) as compared to Pi, but how organoarsenicals (As–C-bond-based compounds) that are produced by alkylation of Asi survive in highly aqueous tissues of marine organisms? We found that this alkylation results in lower hydrolysis rate of Asi diester. Our work concluded that alkylating effort by our body on Asi is to avoid structural ambiguity with phosphate and excrete out arsenic in the form of organoarsenicals from body.
Keywords: ARSENIC
ARSENOBETAINE
ARSENOCHOLINE
ARSENOSUGAR
DMA
MMA
ARSENATE ORGANOARSENICALS
ARSONIC ACID
HYDROLYSIS
URI: http://hdl.handle.net/10995/61843
RSCI ID: https://elibrary.ru/item.asp?id=35559949
ISSN: 2409-5613 (Print)
2411-1414 (Online)
DOI: 10.15826/chimtech.2018.5.2.01
Origin: Chimica Techno Acta. 2018. Vol. 5. № 2
Appears in Collections:Chimica Techno Acta

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