Asymmetric reactions of a series of aromatic azines with nucleophiles

Abstract

Current review is devoted to the reactions of nucleophilic addition in azine series, leading to the stereoselective formation of optically active products. Three types of reactions are reviewed: the reactions of achiral nucleophiles with chiral azines; the reactions of chiral nucleophiles with achiral azines; reactions of achiral nucleophiles with achiral azines in the presence of chiral catalysts. © 2012 The Japan Institute of Heterocyclic Chemistry.