Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/51175
Title: Synthesis of novel 5,6-dihydropyrrolo[2,1-a]isoquinolines via grob reaction between (E)-1,1,1-trifluoro-3-nitro-2-butene and 3,4-dihydroisoquinolines
Authors: Korotaev, Vladislav Y.
Sosnovskikh, Vyacheslav Y.
Barkov, Alexey Y.
Slepukhin, Pavel A.
Shklyaev, Yurii V.
Issue Date: 2012
Citation: Synthesis of novel 5,6-dihydropyrrolo[2,1-a]isoquinolines via grob reaction between (E)-1,1,1-trifluoro-3-nitro-2-butene and 3,4-dihydroisoquinolines / Vladislav Y. Korotaev, Vyacheslav Y. Sosnovskikh, Alexey Y. Barkov, Pavel A. Slepukhin, Yurii V. Shklyaev // Journal of Heterocyclic Chemistry. — 2012. — Vol. 49. — № 4. — P. 856-860.
Abstract: Uncatalyzed cycloaddition of 3,4-dihydroisoquinolines to (E)-1,1,1-trifluoro-3-nitro-2-butene via Grob reaction provide a simple one-step route to the 5,6-dihydropyrrolo[2,1-a]isoquinolines, which represent the basic structural framework of the antitumor active alkaloid crispine. © 2012 HeteroCorporation.
URI: http://hdl.handle.net/10995/51175
https://elar.urfu.ru/handle/10995/51175
Access: info:eu-repo/semantics/restrictedAccess
SCOPUS ID: 84866259761
WOS ID: 000308586900023
PURE ID: 1081227
ISSN: 0022-152X
DOI: 10.1002/jhet.881
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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