Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/31824
Title: 6-Aminotriazolo[1,5-a]pyrimidines as precursors of 1,2,4-triazolo[5,1-b]purines
Authors: Savateev, K. V.
Borisov, S. S.
Voinkov, E. K.
Ulomsky, E. N.
Rusinov, V. L.
Chupakhin, O. N.
Issue Date: 2015
Citation: 6-Aminotriazolo[1,5-a]pyrimidines as precursors of 1,2,4-triazolo[5,1-b]purines / K. V. Savateev, S. S. Borisov, E. K. Voinkov, E. N. Ulomsky, V. L. Rusinov, O. N. Chupakhin // Chimica Techno Acta. — 2015. — Vol. 2. № 2. — С. 127-128.
Abstract: Triazolo[5,1-b]purines are rare structural analogues of natural nucleosides and nucleobases purine series. At the same time, prominent representatives of azolopurines exhibit a broad spectrum of antiviral effect, activity against of rheumatoid arthritis, psoriasis, Alzheimer’s, Parkinson’s and etc. Despite the practical value azolo[5,1-b]purines extremely sparingly represented in the chemical literature, due to the complexity of their synthesis. We suggest a convenient way to synthesize triazolopurines with aminotriazolo[1,5-a]pyrimidines (2) as available starting compounds obtained in good yield by reduction of nitro derivatives (1).
Keywords: 6-AMINOTRIAZOLO[1,5-A]PYRIMIDINES
1,2,4-TRIAZOLO[5,1-B]PURINES
ALZHEIMER'S, PARKINSON'S
REDUCTION OF NITRO FUNCTION
ТРИАЗОЛО[5,1-B]ПУРИНЫ
БОЛЕЗНЬ ПАРКИНСОНА
БОЛЕЗНЬ АЛЬЦГЕЙМЕРА
ВОССТАНОВЛЕНИЕ НИТРОГРУППЫ
URI: http://hdl.handle.net/10995/31824
RSCI ID: https://elibrary.ru/item.asp?id=23785871
ISSN: 2409-5613
Other versions: http://hdl.handle.net/10995/31825
DOI: http://dx.doi.org/10.15826/chimtech.2015.2.2.013
metadata.dc.description.sponsorship: The work was supported by RFBR grant 13-03-0086.
Origin: Chimica Techno Acta. 2015. Vol. 2. № 2.
Appears in Collections:Chimica Techno Acta

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