Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/27459
Title: Benzyne-mediated rearrangement of 3-(2-pyridyl)-1,2,4-triazines into 10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles
Authors: Nikonov, I. L.
Kopchuk, D. S.
Kovalev, I. S.
Zyryanov, G. V.
Khasanov, A. F.
Slepukhin, P. A.
Rusinov, V. L.
Chupakhin, O. N.
Зырянов, Г. В.
Issue Date: 2013
Citation: Benzyne-mediated rearrangement of 3-(2-pyridyl)-1,2,4-triazines into 10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles / I. L. Nikonov, D. S. Kopchuk, I. S. Kovalev [et al.] // Tetrahedron Letters. — 2013. — Vol. 54. — № 48. — P. 6427-6429.
Abstract: The reaction between 5-R-6-R1-3-(2-pyridyl)-1,2,4-triazines and benzyne generated in situ in toluene under reflux results in the formation of 10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles 3 in up to 60% yields instead of the expected 3-R-4-R1-1-(2-pyridyl)isoquinolines 2. The crystal structure of product 3c and the proposed mechanism for the formation of 3 are reported. © 2013 Elsevier Ltd. All rights reserved.
Keywords: 1,2,3-TRIAZOLES
1,2,4-TRIAZINES
ARYNES
PYRIDO[1,2-A]INDOLES
REARRANGEMENT
INDOLE DERIVATIVE
ISOQUINOLINE DERIVATIVE
TRIAZINE DERIVATIVE
ARTICLE
CHEMICAL ANALYSIS
CHEMICAL REACTION
CHEMICAL STRUCTURE
SYNTHESIS
URI: http://hdl.handle.net/10995/27459
SCOPUS ID: 84886786089
WOS ID: 000326613600007
PURE ID: 833955
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2013.09.042
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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