Reaction of 5-aryloxazolidines with arylmagnesium bromides as a new route to N-benzyl-β-hydroxyphenethylamines as starting materials for the preparation of 4-aryl-1,2,3,4-tetrahydroisoquinolines

Moshkin, V. S.; Sosnovskikh, V. Y.

doi:10.1016/j.tetlet.2013.03.076

Please use this identifier to cite or link to this item: http://elar.urfu.ru/handle/10995/27358

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DC Field	Value	Language
dc.contributor.author	Moshkin, V. S.	en
dc.contributor.author	Sosnovskikh, V. Y.	en
dc.date.accessioned	2014-11-29T19:47:01Z	-
dc.date.available	2014-11-29T19:47:01Z	-
dc.date.issued	2013	-
dc.identifier.citation	Moshkin V. S. Reaction of 5-aryloxazolidines with arylmagnesium bromides as a new route to N-benzyl-β-hydroxyphenethylamines as starting materials for the preparation of 4-aryl-1,2,3,4-tetrahydroisoquinolines / V. S. Moshkin, V. Y. Sosnovskikh // Tetrahedron Letters. — 2013. — Vol. 54. — № 21. — P. 2699-2702.	en
dc.identifier.issn	0040-4039	-
dc.identifier.other	1	good_DOI
dc.identifier.other	4eb6bc4a-a840-4a4a-b2ad-0c718aec701d	pure_uuid
dc.identifier.other	http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=84876407076	m
dc.identifier.uri	http://elar.urfu.ru/handle/10995/27358	-
dc.description.abstract	Benzaldehydes react smoothly with the non-stabilized azomethine ylide derived from sarcosine and formaldehyde to form 5-aryloxazolidines as intermediates, which undergo ring-opening to give N-benzyl-β- hydroxyphenethylamines in good yields by the action of arylmagnesium bromides. Their subsequent acid-catalyzed cyclization into 4-aryl-1,2,3,4- tetrahydroisoquinolines was performed in moderate to good yields. © 2013 Elsevier Ltd. All rights reserved.	en
dc.format.mimetype	application/pdf	en
dc.language.iso	en	en
dc.source	Tetrahedron Letters	en
dc.subject	4-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINES	en
dc.subject	5-ARYLOXAZOLIDINES	en
dc.subject	[3+2] CYCLOADDITION	en
dc.subject	CYCLIZATION REACTION	en
dc.subject	NON-STABILIZED AZOMETHINE YLIDE	en
dc.subject	4 ARYL 1,2,3,4 TETRAHYDROISOQUINOLINE	en
dc.subject	5 ARYLOXAZOLIDINE	en
dc.subject	ARYLMAGNESIUM BROMIDE	en
dc.subject	AZOMETHINE YLIDE	en
dc.subject	BENZALDEHYDE DERIVATIVE	en
dc.subject	BROMIDE	en
dc.subject	FORMALDEHYDE	en
dc.subject	N BENZYL BETA HYDROXYPHENETHYLAMINE	en
dc.subject	OXAZOLIDINE DERIVATIVE	en
dc.subject	PHENYLETHANOLAMINE DERIVATIVE	en
dc.subject	SARCOSINE	en
dc.subject	TETRAHYDROISOQUINOLINE DERIVATIVE	en
dc.subject	UNCLASSIFIED DRUG	en
dc.subject	ARTICLE	en
dc.subject	CYCLIZATION	en
dc.subject	RING OPENING	en
dc.title	Reaction of 5-aryloxazolidines with arylmagnesium bromides as a new route to N-benzyl-β-hydroxyphenethylamines as starting materials for the preparation of 4-aryl-1,2,3,4-tetrahydroisoquinolines	en
dc.type	Article	en
dc.type	info:eu-repo/semantics/publishedVersion	en
dc.type	info:eu-repo/semantics/article	en
dc.identifier.doi	10.1016/j.tetlet.2013.03.076	-
dc.identifier.scopus	84876407076	-
local.affiliation	Department of Chemistry, Ural Federal University, prosp. Lenina 51, 620000 Ekaterinburg, Russian Federation	en
local.contributor.employee	Мошкин Владимир Сергеевич	ru
local.contributor.employee	Сосновских Вячеслав Яковлевич	ru
local.description.firstpage	2699	-
local.description.lastpage	2702	-
local.issue	21	-
local.volume	54	-
dc.identifier.wos	000318393000034	-
local.contributor.department	Институт естественных наук и математики	ru
local.identifier.pure	909503	-
local.identifier.eid	2-s2.0-84876407076	-
local.identifier.wos	WOS:000318393000034	-
Appears in Collections:	Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC

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