Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на этот ресурс: http://elar.urfu.ru/handle/10995/27253
Название: Mössbauer spectroscopy of the iron cores in human liver ferritin, ferritin in normal human spleen and ferritin in spleen from patient with primary myelofibrosis: Preliminary results of comparative analysis
Авторы: Oshtrakh, M. I.
Alenkina, I. V.
Vinogradov, A. V.
Konstantinova, T. S.
Kuzmann, E.
Semionkin, V. A.
Дата публикации: 2013
Библиографическое описание: Mössbauer spectroscopy of the iron cores in human liver ferritin, ferritin in normal human spleen and ferritin in spleen from patient with primary myelofibrosis: Preliminary results of comparative analysis / M. I. Oshtrakh, I. V. Alenkina, A. V. Vinogradov [et al.] // BioMetals. — 2013. — Vol. 26. — № 2. — P. 229-239.
Аннотация: Comparative study of human liver ferritin and spleen tissues from healthy human and patient with primary myelofibrosis was carried out using Mössbauer spectroscopy with a high velocity resolution at 295 and 90 K and with a low velocity resolution at 20 K. The results obtained demonstrated that the iron content in patient's spleen in the form of iron storage proteins was about ten times larger than that in normal tissue. However, in the case of patient with primary myelofibrosis the magnetic anisotropy energy barrier differed from that in normal case and, probably, the iron core size was supposed to be slightly larger than that in both normal spleen tissue and normal human liver ferritin in contrast to well-known data for iron overload in patients with thalassemia accompanied by the iron-core size increase. Therefore, the iron overload in the case of patient with primary myelofibrosis may be related to increase in the ferritin content mainly. It was also found that Mössbauer hyperfine parameters for normal and patient's spleen and normal human liver ferritin demonstrated some small differences related, probably, to some small structural variations in the ferritin iron cores of patient's spleen. © 2013 Springer Science+Business Media New York.
Ключевые слова: IRON STORAGE PROTEINS
MÖSSBAUER SPECTROSCOPY
PRIMARY MYELOFIBROSIS
SPLEEN TISSUES
FERRITIN
IRON
ANISOTROPY
ARTICLE
BETA THALASSEMIA
COMPARATIVE STUDY
CONTROLLED STUDY
HUMAN
HUMAN CELL
HUMAN TISSUE
IRON OVERLOAD
IRON STORAGE
LIVER LEVEL
MOSSBAUER SPECTROSCOPY
MYELOID METAPLASIA
ROOM TEMPERATURE
SIGNAL NOISE RATIO
TRANSMISSION ELECTRON MICROSCOPY
FERRITINS
HUMANS
IRON
LIVER
PRIMARY MYELOFIBROSIS
SPECTROSCOPY, MOSSBAUER
SPLEEN
URI: http://elar.urfu.ru/handle/10995/27253
Идентификатор SCOPUS: 84877876769
Идентификатор WOS: 000319802100003
Идентификатор PURE: 915746
ISSN: 0966-0844
DOI: 10.1007/s10534-012-9602-2
Располагается в коллекциях:Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC

Файлы этого ресурса:
Файл Описание РазмерФормат 
scopus-2013-0420.pdf843,88 kBAdobe PDFПросмотреть/Открыть


Все ресурсы в архиве электронных ресурсов защищены авторским правом, все права сохранены.