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  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorBykov, R.en
dc.contributor.authorItani, T.en
dc.contributor.authorStarikova, P.en
dc.contributor.authorSkryabina, S.en
dc.contributor.authorKilyachina, A.en
dc.contributor.authorKoltunov, S.en
dc.contributor.authorRomanov, S.en
dc.contributor.authorSemenov, A.en
dc.date.accessioned2025-02-25T10:52:08Z-
dc.date.available2025-02-25T10:52:08Z-
dc.date.issued2024-
dc.identifier.citationBykov, R., Itani, T., Starikova, P., Skryabina, S., Kilyachina, A., Koltunov, S., Romanov, S., & Semenov, A. (2024). Genetic Diversity and Phylogenetic Relationship of Human Norovirus Sequences Derived from Municipalities within the Sverdlovsk Region of Russia. Viruses, 16(7), [1001]. https://doi.org/10.3390/v16071001apa_pure
dc.identifier.issn1999-4915-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access; Gold Open Access; Green Open Access3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85199612457&doi=10.3390%2fv16071001&partnerID=40&md5=36ac1466be041c4a8c22b1e1f68d8acc1
dc.identifier.otherhttps://www.mdpi.com/1999-4915/16/7/1001/pdf?version=1718968758pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/141669-
dc.description.abstractHuman noroviruses (HuNoVs) are highly contagious pathogens responsible of norovirus-associated acute gastroenteritis (AGE). GII.4 is the prevailing HuNoV genotype worldwide. Currently there are no studies on the molecular monitoring and phylogenetic analysis of HuNoVs in the territory of the Sverdlovsk region; therefore, it is not possible to objectively assess their genetic diversity. The aim of the study is to carry out genotyping and phylogenetic analysis of HuNoVs in the Sverdlovsk region from 2022 to 2023. Fecal samples (n = 510) were collected from children suffering from HuNoV-AGE in municipalities of the Sverdlovsk region and the capsid genotype was determined by amplifying the ORF1/ORF2 junction. Of the 196 HuNoVs typed, which represent 38% of the studied samples, the largest share of HuNoV genotypes belong to the GII genogroup—86%, followed by the GI genogroup—14%. Noroviruses GII.4 and GII.17 were the co-dominant capsid genotypes (33.2% each). Phylogenetic analysis demonstrates that the identified sequences on the territory of the Sverdlovsk region have the smallest genetic distance, which gives grounds for their unification into a common cluster. Routine monitoring and phylogenetic analysis of circulating norovirus pathogens spectrum will enable timely tracking of HuNoVs genetic diversity and evolutionary events. This will lead to the development of more effective anti-epidemic measures, ultimately reducing the burden of infectious diseases. © 2024 by the authors.en
dc.description.sponsorshipRussian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, (123051100045-0)en
dc.description.sponsorshipThis research was funded by the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (scientific study \u2116 123051100045-0).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.sourceViruses2
dc.sourceVirusesen
dc.subjectGENETIC DISTANCEen
dc.subjectGENOGROUP GIIen
dc.subjectGENOTYPINGen
dc.subjectHUMAN NOROVIRUSESen
dc.subjectPHYLOGENETIC ANALYSISen
dc.subjectCALICIVIRIDAE INFECTIONSen
dc.subjectCAPSID PROTEINSen
dc.subjectCHILDen
dc.subjectCITIESen
dc.subjectFECESen
dc.subjectGASTROENTERITISen
dc.subjectGENETIC VARIATIONen
dc.subjectGENOTYPEen
dc.subjectHUMANSen
dc.subjectNOROVIRUSen
dc.subjectPHYLOGENYen
dc.subjectRNA, VIRALen
dc.subjectRUSSIAen
dc.subjectCAPSID PROTEINen
dc.subjectVIRUS RNAen
dc.subjectACUTE GASTROENTERITISen
dc.subjectARTICLEen
dc.subjectCHILDen
dc.subjectENZYME IMMUNOASSAYen
dc.subjectEPIDEMICen
dc.subjectGENE SEQUENCEen
dc.subjectGENETIC ANALYSISen
dc.subjectGENETIC DISTANCEen
dc.subjectGENETIC VARIABILITYen
dc.subjectGENOTYPEen
dc.subjectGENOTYPINGen
dc.subjectHUMANen
dc.subjectINCIDENCEen
dc.subjectNONHUMANen
dc.subjectNOROVIRUSen
dc.subjectNOROVIRUS INFECTIONen
dc.subjectPHYLOGENYen
dc.subjectPOLYMERASE CHAIN REACTIONen
dc.subjectRUSSIAN FEDERATIONen
dc.subjectCALICIVIRUS INFECTIONen
dc.subjectCITYen
dc.subjectCLASSIFICATIONen
dc.subjectEPIDEMIOLOGYen
dc.subjectFECESen
dc.subjectGASTROENTERITISen
dc.subjectGENETIC VARIATIONen
dc.subjectGENETICSen
dc.subjectGENOTYPEen
dc.subjectISOLATION AND PURIFICATIONen
dc.subjectVIROLOGYen
dc.titleGenetic Diversity and Phylogenetic Relationship of Human Norovirus Sequences Derived from Municipalities within the Sverdlovsk Region of Russiaen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/v16071001-
dc.identifier.scopus85199612457-
local.contributor.employeeBykov R., Federal Budgetary Institution of Science, «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, 620030, Russian Federationen
local.contributor.employeeItani T., Federal Budgetary Institution of Science, «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, 620030, Russian Federationen
local.contributor.employeeStarikova P., Federal Budgetary Institution of Science, «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, 620030, Russian Federationen
local.contributor.employeeSkryabina S., Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing in the Sverdlovsk Region, Ekaterinburg, 620078, Russian Federationen
local.contributor.employeeKilyachina A., Federal Budgetary Healthcare Institution «Center of Hygiene and Epidemiology in the Sverdlovsk Region», Ekaterinburg, 620078, Russian Federationen
local.contributor.employeeKoltunov S., Federal Budgetary Healthcare Institution «Center of Hygiene and Epidemiology in the Sverdlovsk Region», Ekaterinburg, 620078, Russian Federationen
local.contributor.employeeRomanov S., Federal Budgetary Healthcare Institution «Center of Hygiene and Epidemiology in the Sverdlovsk Region», Ekaterinburg, 620078, Russian Federationen
local.contributor.employeeSemenov A., Federal Budgetary Institution of Science, «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, 620030, Russian Federation, Department of Medical Microbiology and Clinical Laboratory Diagnostics, Ural State Medical University, Ekaterinburg, 620109, Russian Federation, Institute of Natural Sciences and Mathematics, Ural Federal University Named after the First President of Russia B.N. Yeltsin, Ekaterinburg, 620075, Russian Federationen
local.issue7-
local.volume16-
dc.identifier.wos001277530800001-
local.contributor.departmentFederal Budgetary Institution of Science, «Federal Scientific Research Institute of Viral Infections «Virome»», Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, 620030, Russian Federationen
local.contributor.departmentFederal Service for Surveillance on Consumer Rights Protection and Human Wellbeing in the Sverdlovsk Region, Ekaterinburg, 620078, Russian Federationen
local.contributor.departmentFederal Budgetary Healthcare Institution «Center of Hygiene and Epidemiology in the Sverdlovsk Region», Ekaterinburg, 620078, Russian Federationen
local.contributor.departmentDepartment of Medical Microbiology and Clinical Laboratory Diagnostics, Ural State Medical University, Ekaterinburg, 620109, Russian Federationen
local.contributor.departmentInstitute of Natural Sciences and Mathematics, Ural Federal University Named after the First President of Russia B.N. Yeltsin, Ekaterinburg, 620075, Russian Federationen
local.identifier.pure61526551-
local.description.order1001
local.identifier.eid2-s2.0-85199612457-
local.fund.rsfRussian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, (123051100045-0)
local.fund.rsfThis research was funded by the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (scientific study \u2116 123051100045-0).
local.identifier.wosWOS:001277530800001-
local.identifier.pmid39066164-
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