1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorKolesnikova, T. O.en
dc.contributor.authorDemin, K. A.en
dc.contributor.authorCosta, F. V.en
dc.contributor.authorZabegalov, K. N.en
dc.contributor.authorde Abreu, M. S.en
dc.contributor.authorGerasimova, E. V.en
dc.contributor.authorKalueff, A. V.en
dc.date.accessioned2024-04-08T11:05:56Z-
dc.date.available2024-04-08T11:05:56Z-
dc.date.issued2022-
dc.identifier.citationKolesnikova, TO, Demin, KA, Costa, FV, Zabegalov, KN, de Abreu, MS, Gerasimova, EV & Kalueff, AV 2022, 'Towards Zebrafish Models of CNS Channelopathies', International Journal of Molecular Sciences, Том. 23, № 22, 13979. https://doi.org/10.3390/ijms232213979harvard_pure
dc.identifier.citationKolesnikova, T. O., Demin, K. A., Costa, F. V., Zabegalov, K. N., de Abreu, M. S., Gerasimova, E. V., & Kalueff, A. V. (2022). Towards Zebrafish Models of CNS Channelopathies. International Journal of Molecular Sciences, 23(22), [13979]. https://doi.org/10.3390/ijms232213979apa_pure
dc.identifier.issn1661-6596-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access; Gold Open Access; Green Open Access3
dc.identifier.otherhttps://www.mdpi.com/1422-0067/23/22/13979/pdf?version=16682490111
dc.identifier.otherhttps://www.mdpi.com/1422-0067/23/22/13979/pdf?version=1668249011pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/131237-
dc.description.abstractChannelopathies are a large group of systemic disorders whose pathogenesis is associated with dysfunctional ion channels. Aberrant transmembrane transport of K+, Na+, Ca2+ and Cl− by these channels in the brain induces central nervous system (CNS) channelopathies, most commonly including epilepsy, but also migraine, as well as various movement and psychiatric disorders. Animal models are a useful tool for studying pathogenesis of a wide range of brain disorders, including channelopathies. Complementing multiple well-established rodent models, the zebrafish (Danio rerio) has become a popular translational model organism for neurobiology, psychopharmacology and toxicology research, and for probing mechanisms underlying CNS pathogenesis. Here, we discuss current prospects and challenges of developing genetic, pharmacological and other experimental models of major CNS channelopathies based on zebrafish. © 2022 by the authors.en
dc.description.sponsorshipApplied Genetics MIPT, (075-15-2021-684)en
dc.description.sponsorshipSPSU, (93020614)en
dc.description.sponsorshipSirius University, (NRB-RND-2116)en
dc.description.sponsorshipFunding text 1: The research partially used the facilities and equipment of the Resource Fund of Applied Genetics MIPT (support grant 075-15-2021-684). A.V.K.’s contribution was partially supported by the SPSU funding program (Project ID 93020614).en
dc.description.sponsorshipFunding text 2: The study is supported by Sirius University budgetary funds (Project ID NRB-RND-2116).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceInternational Journal of Molecular Sciences2
dc.sourceInternational Journal of Molecular Sciencesen
dc.subjectANIMAL MODELen
dc.subjectBRAINen
dc.subjectCHANNELOPATHYen
dc.subjectION CHANNELen
dc.subjectZEBRAFISHen
dc.subjectANIMALSen
dc.subjectBRAINen
dc.subjectCHANNELOPATHIESen
dc.subjectDISEASE MODELS, ANIMALen
dc.subjectEPILEPSYen
dc.subjectZEBRAFISHen
dc.subjectCENTRAL NERVOUS SYSTEM AGENTSen
dc.subjectION CHANNELen
dc.subjectANIMAL MODELen
dc.subjectCENTRAL NERVOUS SYSTEM CHANNELOPATHYen
dc.subjectCENTRAL NERVOUS SYSTEM DISEASEen
dc.subjectEXPERIMENTAL DESIGNen
dc.subjectEXPERIMENTAL MODELen
dc.subjectGENETICSen
dc.subjectNEURONAL CHANNELOPATHYen
dc.subjectNEUROPATHOLOGYen
dc.subjectNONHUMANen
dc.subjectREVIEWen
dc.subjectZEBRA FISHen
dc.subjectANIMALen
dc.subjectBRAINen
dc.subjectCHANNELOPATHYen
dc.subjectDISEASE MODELen
dc.subjectEPILEPSYen
dc.subjectZEBRA FISHen
dc.titleTowards Zebrafish Models of CNS Channelopathiesen
dc.typeReviewen
dc.typeinfo:eu-repo/semantics/reviewen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/ijms232213979-
dc.identifier.scopus85142788186-
local.contributor.employeeKolesnikova T.O., Neurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federationen
local.contributor.employeeDemin K.A., Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, 199034, Russian Federation, Institute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, St. Petersburg, 197341, Russian Federationen
local.contributor.employeeCosta F.V., Neurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federationen
local.contributor.employeeZabegalov K.N., Neurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federationen
local.contributor.employeede Abreu M.S., Moscow Institute of Physics and Technology, Moscow, 141701, Russian Federationen
local.contributor.employeeGerasimova E.V., Neurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federationen
local.contributor.employeeKalueff A.V., Neurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federation, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, 199034, Russian Federation, Institute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, St. Petersburg, 197341, Russian Federation, Moscow Institute of Physics and Technology, Moscow, 141701, Russian Federation, Laboratory of Preclinical Bioscreening, Granov Russian Research Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, St. Petersburg, 197758, Russian Federation, Ural Federal University, Yekaterinburg, 620002, Russian Federation, Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, 630117, Russian Federationen
local.issue22-
local.volume23-
dc.identifier.wos000887378400001-
local.contributor.departmentNeurobiology Program, Sirius University of Science and Technology, Sochi, 354349, Russian Federationen
local.contributor.departmentInstitute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, 199034, Russian Federationen
local.contributor.departmentInstitute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, St. Petersburg, 197341, Russian Federationen
local.contributor.departmentMoscow Institute of Physics and Technology, Moscow, 141701, Russian Federationen
local.contributor.departmentLaboratory of Preclinical Bioscreening, Granov Russian Research Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, St. Petersburg, 197758, Russian Federationen
local.contributor.departmentUral Federal University, Yekaterinburg, 620002, Russian Federationen
local.contributor.departmentScientific Research Institute of Neurosciences and Medicine, Novosibirsk, 630117, Russian Federationen
local.identifier.pure32802257-
local.identifier.pure49af393d-6b99-4c2d-b41f-b3921519982euuid
local.description.order13979-
local.identifier.eid2-s2.0-85142788186-
local.identifier.wosWOS:000887378400001-
local.identifier.pmid36430455-
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