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dc.contributor.authorAluru, R.en
dc.contributor.authorMukherjee, A.en
dc.contributor.authorZyryanov, G. V.en
dc.contributor.authorMajee, A.en
dc.contributor.authorSantra, S.en
dc.date.accessioned2024-04-05T16:35:09Z-
dc.date.available2024-04-05T16:35:09Z-
dc.date.issued2023-
dc.identifier.citationAluru, R, Mukherjee, A, Zyryanov, G, Majee, A & Santra, S 2023, 'Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones', Current Issues in Molecular Biology, Том. 45, № 10, стр. 8461-8475. https://doi.org/10.3390/cimb45100533harvard_pure
dc.identifier.citationAluru, R., Mukherjee, A., Zyryanov, G., Majee, A., & Santra, S. (2023). Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones. Current Issues in Molecular Biology, 45(10), 8461-8475. https://doi.org/10.3390/cimb45100533apa_pure
dc.identifier.issn1467-3037-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Gold, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85175087801&doi=10.3390%2fcimb45100533&partnerID=40&md5=252b8eb5e8dd2820b558c690dfc0ff951
dc.identifier.otherhttps://www.mdpi.com/1467-3045/45/10/533/pdf?version=1697692167pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/130896-
dc.description.abstractNatural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial, antidiabetic, anti-inflammatory, antiviral and neuroprotective effects. In addition, various studies have revealed that aurones are potential templates for the regulation of diabetes mellitus and its associated complications. Likewise, certain aurones and their analogues have been found to be remarkable kinase inhibitors of DARK2, PPAR-γ, PTPM1, AGE, α-amylase and α-glucosidase, which represents a promising approach for the treatment of chronic metabolic disorders such as diabetes. Therefore, in our present study, we provide a detailed account of the advances in aurones as antidiabetic agents over the past decade. © 2023 by the authors.en
dc.description.sponsorshipMinistry of Education and Science of the Russian Federation, Minobrnaukaen
dc.description.sponsorshipThis research was funded by the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceCurrent Issues in Molecular Biology2
dc.sourceCurrent Issues in Molecular Biologyen
dc.subjectANTIDIABETICen
dc.subjectAURONESen
dc.subjectCHALCONEen
dc.subjectFLAVONOIDSen
dc.subjectΑ-GLUCOSIDASE INHIBITORen
dc.subjectAMYLASEen
dc.subjectANTIDIABETIC AGENTen
dc.subjectAURONEen
dc.subjectCHALCONE DERIVATIVEen
dc.subjectETHYLENE OXIDE DERIVATIVEen
dc.subjectFLAVANOIDen
dc.subjectFLAVONE DERIVATIVEen
dc.subjectGLUCOSIDASEen
dc.subjectNATURAL PRODUCTen
dc.subjectPEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMAen
dc.subjectUNCLASSIFIED DRUGen
dc.subjectANNULATION REACTIONen
dc.subjectANTIDIABETIC ACTIVITYen
dc.subjectANTIINFLAMMATORY ACTIVITYen
dc.subjectANTIMICROBIAL ACTIVITYen
dc.subjectANTINEOPLASTIC ACTIVITYen
dc.subjectANTIOXIDANT ACTIVITYen
dc.subjectANTIVIRAL ACTIVITYen
dc.subjectBIOLOGICAL ACTIVITYen
dc.subjectBIOSYNTHESISen
dc.subjectCYCLIZATIONen
dc.subjectDIABETES MELLITUSen
dc.subjectDRUG DEVELOPMENTen
dc.subjectDRUG SYNTHESISen
dc.subjectGLUCOSE ABSORPTIONen
dc.subjectGLUCOSE METABOLISMen
dc.subjectHUMANen
dc.subjectHYPERGLYCEMIAen
dc.subjectIC50en
dc.subjectMETABOLIC DISORDERen
dc.subjectNEUROPROTECTIONen
dc.subjectREVIEWen
dc.subjectSIGNAL TRANSDUCTIONen
dc.titleRecent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Auronesen
dc.typeReviewen
dc.typeinfo:eu-repo/semantics/reviewen
dc.type|info:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/cimb45100533-
dc.identifier.scopus85175087801-
local.contributor.employeeAluru, R., Chemical Engineering Institute, Ural Federal University, 19 Mira Str, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeMukherjee, A., Chemical Engineering Institute, Ural Federal University, 19 Mira Str, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeZyryanov, G.V., Chemical Engineering Institute, Ural Federal University, 19 Mira Str, Yekaterinburg, 620002, Russian Federation, I. Ya. Postovsky Institute of Organic Synthesis of RAS, Ural Division, 22/20 S. Kovalevskoy/Akademicheskaya Str, Yekaterinburg, 620219, Russian Federationen
local.contributor.employeeMajee, A., Department of Chemistry, Visva-Bharati (A Central University), Birbhum, Santiniketan731235, Indiaen
local.contributor.employeeSantra, S., Chemical Engineering Institute, Ural Federal University, 19 Mira Str, Yekaterinburg, 620002, Russian Federationen
local.description.firstpage8461-
local.description.lastpage8475-
local.issue10-
local.volume45-
dc.identifier.wos001098241800001-
local.contributor.departmentChemical Engineering Institute, Ural Federal University, 19 Mira Str, Yekaterinburg, 620002, Russian Federationen
local.contributor.departmentI. Ya. Postovsky Institute of Organic Synthesis of RAS, Ural Division, 22/20 S. Kovalevskoy/Akademicheskaya Str, Yekaterinburg, 620219, Russian Federationen
local.contributor.departmentDepartment of Chemistry, Visva-Bharati (A Central University), Birbhum, Santiniketan731235, Indiaen
local.identifier.pure47647488-
local.identifier.eid2-s2.0-85175087801-
local.identifier.wosWOS:001098241800001-
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