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dc.contributor.authorMinigalieva, I. A.en
dc.contributor.authorRyabova, Y. V.en
dc.contributor.authorShelomencev, I. G.en
dc.contributor.authorAmromin, L. A.en
dc.contributor.authorMinigalieva, R. F.en
dc.contributor.authorSutunkova, Y. M.en
dc.contributor.authorPrivalova, L. I.en
dc.contributor.authorSutunkova, M. P.en
dc.date.accessioned2024-04-05T16:16:30Z-
dc.date.available2024-04-05T16:16:30Z-
dc.date.issued2023-
dc.identifier.citationMinigalieva, IA, Ryabova, YV, Shelomencev, IG, Amromin, LA, Minigalieva, RF, Sutunkova, YM, Privalova, LI & Sutunkova, MP 2023, 'Analysis of Experimental Data on Changes in Various Structures and Functions of the Rat Brain following Intranasal Administration of Fe2O3 Nanoparticles', International Journal of Molecular Sciences, Том. 24, № 4, 3572. https://doi.org/10.3390/ijms24043572harvard_pure
dc.identifier.citationMinigalieva, I. A., Ryabova, Y. V., Shelomencev, I. G., Amromin, L. A., Minigalieva, R. F., Sutunkova, Y. M., Privalova, L. I., & Sutunkova, M. P. (2023). Analysis of Experimental Data on Changes in Various Structures and Functions of the Rat Brain following Intranasal Administration of Fe2O3 Nanoparticles. International Journal of Molecular Sciences, 24(4), [3572]. https://doi.org/10.3390/ijms24043572apa_pure
dc.identifier.issn1661-6596-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Gold, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85149053000&doi=10.3390%2fijms24043572&partnerID=40&md5=c0c82763c119fdc24cfed04d9b549a0a1
dc.identifier.otherhttps://www.mdpi.com/1422-0067/24/4/3572/pdf?version=1676020978pdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/130238-
dc.description.abstractParticulate matter, including iron nanoparticles, is one of the constituents of ambient air pollution. We assessed the effect of iron oxide (Fe2O3) nanoparticles on the structure and function of the brain of rats. Electron microscopy showed Fe2O3 nanoparticles in the tissues of olfactory bulbs but not in the basal ganglia of the brain after their subchronic intranasal administration. We observed an increase in the number of axons with damaged myelin sheaths and in the proportion of pathologically altered mitochondria in the brains of the exposed animals against the background of almost stable blood parameters. We conclude that the central nervous system can be a target for toxicity of low-dose exposure to Fe2O3 nanoparticles. © 2023 by the authors.en
dc.description.sponsorshipMinistry of Education and Science of the Russian Federation, Minobrnauka; Ural Federal University, UrFUen
dc.description.sponsorshipThe analysis was supported by the Ministry of Science and Higher Education of the Russian Federation within the “Priority—2030” Development Program of the Ural Federal University; the experimental data were provided by Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceInternational Journal of Molecular Sciences2
dc.sourceInternational Journal of Molecular Sciencesen
dc.subjectELECTRON MICROSCOPYen
dc.subjectKINETICS OF NANOPARTICLESen
dc.subjectNEUROTOXICITYen
dc.subjectIRON OXIDE NANOPARTICLEen
dc.subjectFERRIC IONen
dc.subjectNANOPARTICLEen
dc.subjectABNORMAL ANIMAL BEHAVIORen
dc.subjectANIMAL EXPERIMENTen
dc.subjectANIMAL TISSUEen
dc.subjectARTICLEen
dc.subjectAXONAL INJURYen
dc.subjectBASAL GANGLIONen
dc.subjectBEHAVIOR DISORDERen
dc.subjectBLOODen
dc.subjectBRAIN FUNCTIONen
dc.subjectBRAIN INJURYen
dc.subjectBRAIN MITOCHONDRIONen
dc.subjectBRAIN TISSUEen
dc.subjectCENTRAL NERVOUS SYSTEMen
dc.subjectCONTROLLED STUDYen
dc.subjectDATA ANALYSISen
dc.subjectDEMYELINATIONen
dc.subjectELECTRON MICROSCOPYen
dc.subjectEXPERIMENTAL STUDYen
dc.subjectEXPLORATORY BEHAVIORen
dc.subjectFEMALEen
dc.subjectHOLE BOARD TESTen
dc.subjectMITOCHONDRIAL TOXICITYen
dc.subjectMYELIN SHEATHen
dc.subjectNANOTOXICOLOGYen
dc.subjectNEUROPATHOLOGYen
dc.subjectNEUROTOXICITYen
dc.subjectNONHUMANen
dc.subjectOLFACTORY BULBen
dc.subjectRATen
dc.subjectULTRASTRUCTUREen
dc.subjectANIMALen
dc.subjectBRAINen
dc.subjectCHEMISTRYen
dc.subjectINTRANASAL DRUG ADMINISTRATIONen
dc.subjectMETABOLISMen
dc.subjectMITOCHONDRIONen
dc.subjectADMINISTRATION, INTRANASALen
dc.subjectANIMALSen
dc.subjectBASAL GANGLIAen
dc.subjectBRAINen
dc.subjectFERRIC COMPOUNDSen
dc.subjectMITOCHONDRIAen
dc.subjectNANOPARTICLESen
dc.subjectRATSen
dc.titleAnalysis of Experimental Data on Changes in Various Structures and Functions of the Rat Brain following Intranasal Administration of Fe2O3 Nanoparticlesen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.type|info:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.3390/ijms24043572-
dc.identifier.scopus85149053000-
local.contributor.employeeMinigalieva, I.A., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federation, Laboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeRyabova, Y.V., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federation, Laboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeShelomencev, I.G., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federationen
local.contributor.employeeAmromin, L.A., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federationen
local.contributor.employeeMinigalieva, R.F., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federation, Laboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeSutunkova, Y.M., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federation, Laboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeePrivalova, L.I., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federation, Laboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeSutunkova, M.P., Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federationen
local.issue4-
local.volume24-
dc.identifier.wos000939322400001-
local.contributor.departmentYekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 30 Popov Street, Yekaterinburg, 620014, Russian Federationen
local.contributor.departmentLaboratory of Stochastic Transport of Nanoparticles in Living Systems, Laboratory of Multi-Scale Mathematical Modeling, Ural Federal University, 51 Lenin Avenue, Yekaterinburg, 620002, Russian Federationen
local.identifier.pure35511491-
local.description.order3572-
local.identifier.eid2-s2.0-85149053000-
local.identifier.wosWOS:000939322400001-
local.identifier.pmid36834983-
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