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  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorKrasnov, V. P.en
dc.contributor.authorLevit, G. L.en
dc.contributor.authorMusiyak, V. V.en
dc.contributor.authorGruzdev, D. A.en
dc.contributor.authorCharushin, V. N.en
dc.date.accessioned2022-10-19T05:22:42Z-
dc.date.available2022-10-19T05:22:42Z-
dc.date.issued2020-
dc.identifier.citationFragment-based approach to novel bioactive purine derivatives / V. P. Krasnov, G. L. Levit, V. V. Musiyak et al. // Pure and Applied Chemistry. — 2020. — Vol. 92. — Iss. 8. — P. 1277-1295.en
dc.identifier.issn334545-
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85091368206&doi=10.1515%2fpac-2019-1214&partnerID=40&md5=de015c95044bce1b93b976fc7996a35flink
dc.identifier.urihttp://elar.urfu.ru/handle/10995/118134-
dc.description.abstractUsing purine as a scaffold, the methods for preparation of novel 2-aminopurine and purine derivatives substituted at position C6 by the fragments of natural amino acids, short peptides, andN-heterocycles, including enantiopure ones, have been proposed. The methods for determination of the enantiomeric purity of the obtained chiral compounds have been developed. Conjugates exhibiting high antimycobacterial or antiherpesvirus activity against both laboratory and multidrug-resistant strains were revealed among the obtained compounds. © 2020 De Gruyter. All rights reserved.en
dc.description.sponsorshipRussian Science Foundation, RSF: 19-13-00231en
dc.description.sponsorshipFunding : The reviewed studies were financially supported by the Russian Science Foundation (project no. 19-13-00231).en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherDe Gruyter Open Ltden
dc.relationinfo:eu-repo/grantAgreement/RSF//19-13-00231en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourcePure and Applied Chemistryen
dc.subjectAMINESen
dc.subjectAMINO ACIDSen
dc.subjectANTITUBERCULAR ACTIVITYen
dc.subjectANTIVIRAL ACTIVITYen
dc.subjectBIOACTIVE MOLECULESen
dc.subjectCOUPLING REACTIONSen
dc.subjectDRUG DESIGNen
dc.subjectMENDELEEV-21en
dc.subjectNUCLEOPHILIC SUBSTITUTION REACTIONSen
dc.subjectORGANIC SYNTHESISen
dc.subjectSTEREOCHEMISTRYen
dc.subjectCHEMICAL ENGINEERINGen
dc.subjectCHEMISTRYen
dc.subject2-AMINOPURINEen
dc.subjectANTI-MYCOBACTERIALen
dc.subjectCHIRAL COMPOUNDSen
dc.subjectENANTIOMERIC PURITYen
dc.subjectMULTIDRUG RESISTANTSen
dc.subjectN-HETEROCYCLESen
dc.subjectNATURAL AMINO ACIDSen
dc.subjectPURINE DERIVATIVESen
dc.subjectSCAFFOLDSen
dc.titleFragment-based approach to novel bioactive purine derivativesen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1515/pac-2019-1214-
dc.identifier.scopus85091368206-
local.contributor.employeeKrasnov, V.P., Russian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federation, Ural Federal University Named after First President of Russia B N Yeltsin, Institute of Chemical Engineering, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeLevit, G.L., Russian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federationen
local.contributor.employeeMusiyak, V.V., Russian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federationen
local.contributor.employeeGruzdev, D.A., Russian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federation, Ural Federal University Named after First President of Russia B N Yeltsin, Institute of Chemical Engineering, Yekaterinburg, 620002, Russian Federationen
local.contributor.employeeCharushin, V.N., Russian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federation, Ural Federal University Named after First President of Russia B N Yeltsin, Institute of Chemical Engineering, Yekaterinburg, 620002, Russian Federationen
local.description.firstpage1277-
local.description.lastpage1295-
local.issue8-
local.volume92-
dc.identifier.wos000560550000008-
local.contributor.departmentRussian Academy of Sciences Ural Branch, Postovsky Institute of Organic Synthesis, 22/20 S.Kovalevskoy/Akademicheskaya St., Yekaterinburg, 620108, Russian Federationen
local.contributor.departmentUral Federal University Named after First President of Russia B N Yeltsin, Institute of Chemical Engineering, Yekaterinburg, 620002, Russian Federationen
local.identifier.pure13696949-
local.identifier.eid2-s2.0-85091368206-
local.fund.rsf19-13-00231-
local.identifier.wosWOS:000560550000008-
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