Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/118098
Title: Mechanical Force Acting on Ferrogel in a Non-Uniform Magnetic Field: Measurements and Modeling
Authors: Blyakhman, F. A.
Safronov, A. P.
Zubarev, A. Y.
Melnikov, G. Y.
Sokolov, S. Y.
Larrañaga, Varga, A.
Kurlyandskaya, G. V.
Issue Date: 2022
Publisher: MDPI
Citation: Mechanical Force Acting on Ferrogel in a Non-Uniform Magnetic Field: Measurements and Modeling / F. A. Blyakhman, A. P. Safronov, A. Y. Zubarev et al. // Micromachines. — 2022. — Vol. 13. — Iss. 8. — 1165.
Abstract: The development of magnetoactive microsystems for targeted drug delivery, magnetic biodetection, and replacement therapy is an important task of present day biomedical research. In this work, we experimentally studied the mechanical force acting in cylindrical ferrogel samples due to the application of a non-uniform magnetic field. A commercial microsystem is not available for this type of experimental study. Therefore, the original experimental setup for measuring the mechanical force on ferrogel in a non-uniform magnetic field was designed, calibrated, and tested. An external magnetic field was provided by an electromagnet. The maximum intensity at the surface of the electromagnet was 39.8 kA/m and it linearly decreased within 10 mm distance from the magnet. The Ferrogel samples were based on a double networking polymeric structure which included a chemical network of polyacrylamide and a physical network of natural polysaccharide guar. Magnetite particles, 0.25 micron in diameter, were embedded in the hydrogel structure, up to 24% by weight. The forces of attraction between an electromagnet and cylindrical ferrogel samples, 9 mm in height and 13 mm in diameter, increased with field intensity and the concentration of magnetic particles, and varied within 0.1–30 mN. The model provided a fair evaluation of the mechanical forces that emerged in ferrogel samples placed in a non-uniform magnetic field and proved to be useful for predicting the deformation of ferrogels in practical bioengineering applications. © 2022 by the authors.
Keywords: ATTRACTIVE FORCE
BIOMEDICAL APPLICATIONS
BIOMIMETIC MATERIALS
FERROGELS
MAGNETIC FIELD
MAGNETIC PARTICLES
MODELING
BIOMIMETICS
CONTROLLED DRUG DELIVERY
ELECTROMAGNETIC FIELD EFFECTS
ELECTROMAGNETS
FUNCTIONAL POLYMERS
MAGNETITE
MICROSYSTEMS
TARGETED DRUG DELIVERY
ATTRACTIVE FORCE
BIOMEDICAL APPLICATIONS
FERROGELS
MAGNETIC FIELD MODELS
MAGNETIC FIELDS MEASUREMENTS
MAGNETIC PARTICLE
MAGNETIC-FIELD
MECHANICAL FORCE
MODELING
NONUNIFORM MAGNETIC FIELDS
MEDICAL APPLICATIONS
URI: http://hdl.handle.net/10995/118098
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85137602695
ISSN: 2072666X
DOI: 10.3390/mi13081165
metadata.dc.description.sponsorship: Ministry of Education and Science of the Russian Federation, Minobrnauka: FEUZ-2020-0051; Russian Science Foundation, RSF: 20-12-00031; Ministry of Health of the Russian Federation: 121032300335-1
This study was in part supported by the program of the Ministry of Health of the Russian Federation (project 121032300335-1). A.Yu. Zubarev and A.P. Safronov acknowledge the financial support of the Russian Science Foundation for theoretical modeling and the numerical verification of the model (grant 20-12-00031). This work was in part financially supported by (G.V. Kurlyandskaya and G.Yu. Melnikov) the Ministry of Science and Higher Education of the Russian Federation (grant number FEUZ-2020-0051).
RSCF project card: 20-12-00031
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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