Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/111845
Title: Cardiovascular and Metabolic Disorders Associated with Occupational Lung Fibrosis in Employees Exposed to the Dust at the Workplace
Authors: Obukhova, T. Yu.
Gurvich, V. B.
Budkar, L. N.
Ustyantsev, S. L.
Solodushkin, S. I.
Karpova, E. A.
Shmonina, O. G.
Issue Date: 2020
Publisher: Izdatel'stvo Meditsina
Federal Scientific Center for Hygiene F.F.Erisman
Citation: Cardiovascular and Metabolic Disorders Associated with Occupational Lung Fibrosis in Employees Exposed to the Dust at the Workplace / T. Yu. Obukhova, V. B. Gurvich, L. N. Budkar et al. // Gigiena i Sanitariya. — 2020. — Vol. 99. — Iss. 1. — P. 97-102.
Abstract: Introduction. The attribution of certain medical conditions in industrial workers to hazardous exposures at the workplace remains a challenging issue of occupational health. Material and methods. In order to identify cardiovascular conditions associated with occupational lung diseases in workers exposed to fibrogenic dust, we conducted a medical check-up examination of individuals employed in refractory production and asbestos industry. The main group consisted of the patients with a confirmed diagnosis of lung fibrosis (asbestosis, silicosis); the reference group was age- and tenure-matched workers without occupational fibrosis. Results. We e stablished a significantly h igher prevalence of arterial hypertension, left ventricular hypertrophy, s inus tachycardia, obesity, hypertriglyceridemia and impaired fasting glycemia in workers with silicosis and asbestosis if compared to those without work-related diseases. Based on the relative risk and attributable fraction estimates, we assume there is moderate occupational causation for arterial hypertension and a strong one for left ventricular hypertrophy, sinus tachycardia, and obesity. Very strong causation was found between occupational exposure to fibrogenic dust and carbohydrate metabolism disorders. High-stage hypertension, dyslipidemia and left ventricular hypertrophy were found to have a statistically significant impact on the timing of silicosis. Whereas high-stage hypertension, coronary artery disease, left ventricular hypertrophy and obesity were found to impact the timing of asbestosis. Conclusion. Cardiovascular and metabolic disorders are statistically more occurrent in workers with silicosis or asbestosis. Therefore, the disease can be regarded as work-related. We established cardiovascular and metabolic disorders to have a statistically significant impact on the timing of silicosis and asbestosis. Therefore, a timely CVD prophylaxis could reduce the risk of occupational lung fibrosis in workers exposed to fibrogenic dust. © 2020 Izdatel'stvo Meditsina. All rights reserved.
Keywords: ASBESTOSIS
CARDIOVASCULAR DISEASES
FIBROGENIC DUST
OCCUPATIONAL DISEASES
SILICOSIS
URI: http://hdl.handle.net/10995/111845
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85081228636
PURE ID: 12262657
ISSN: 0016-9900
metadata.dc.description.sponsorship: The work of Solodushkin was supported by Act 211 Government of the Russian Federation, contract No 02.A03.21.0006.
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

Files in This Item:
File Description SizeFormat 
2-s2.0-85081228636.pdf536,52 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.