1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorPanov, V.en
dc.contributor.authorBushueva, T.en
dc.contributor.authorMinigalieva, I.en
dc.contributor.authorNaumova, A.en
dc.contributor.authorShur, V.en
dc.contributor.authorShishkina, E.en
dc.contributor.authorSutunkova, M.en
dc.contributor.authorGurviсh, V.en
dc.contributor.authorPrivalova, L.en
dc.contributor.authorKatsnelson, B.en
dc.date.accessioned2022-05-12T08:22:46Z-
dc.date.available2022-05-12T08:22:46Z-
dc.date.issued2021-
dc.identifier.citationNew Data on Variously Directed Dose-Response Relationships and the Combined Action Types for Different Outcomes of in Vitro Nanoparticle Cytotoxicity / V. Panov, T. Bushueva, I. Minigalieva et al. // Dose-Response. — 2021. — Vol. 19. — Iss. 4. — P. .en
dc.identifier.issn1559-3258-
dc.identifier.otherAll Open Access, Gold, Green3
dc.identifier.urihttp://elar.urfu.ru/handle/10995/111776-
dc.description.abstractSpherical selenium-oxide and copper-oxide nanoparticles (SeO-NP with mean diameter 51 ± 14 nm and CuO-NP with mean diameter 21 ± 4 nm) were found to be cytotoxic for human fibroblast-like cells in vitro, as judged by decreased ATP-dependent luminescence. Compared with SeO-NP, CuO-NP produced a somewhat stronger effect of this kind. Along with cell hypertrophy developing in response to certain doses of SeO-NP and CuO-NP, our experiment also revealed doses causing a decrease in cell and cell-nucleus sizes. We observed both monotonic and different variants of nonmonotonic dose-response relationship. For the latter, we have succeeded in constructing adequate mathematical expressions based on the generalized hormesis paradigm that we had considered previously in respect of CdS-NP and PbS-NP cytotoxicity for cardiomyocites. It was demonstrated as well that combined toxicity of SeO-NP and CuO-NP is of different types depending on the outcome. © The Author(s) 2021.en
dc.description.sponsorshipThe author(s) received no financial support for the research, authorship, and/or publication of this article. The equipment of the Ural Center for Shared Use "Modern nanotechnology" Ural Federal University (Reg.& numero; 2968) was used.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherSAGE Publications Inc.en1
dc.publisherSAGE Publicationsen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceDose-Resp.2
dc.sourceDose-Responseen
dc.subjectCOPPER-OXIDEen
dc.subjectDOSE-RESPONSE RELATIONSHIPSen
dc.subjectHORMESISen
dc.subjectNANOPARTICLESen
dc.subjectSELENIUM-OXIDEen
dc.subjectCOPPER OXIDEen
dc.subjectNANOPARTICLEen
dc.subjectSELENIUM OXIDEen
dc.subjectARTICLEen
dc.subjectBIOLUMINESCENCEen
dc.subjectCELL CULTUREen
dc.subjectCYTOTOXICITYen
dc.subjectENERGY DISPERSIVE X RAY SPECTROSCOPYen
dc.subjectHORMESISen
dc.subjectIN VITRO STUDYen
dc.titleNew Data on Variously Directed Dose-Response Relationships and the Combined Action Types for Different Outcomes of in Vitro Nanoparticle Cytotoxicityen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.rsi47533692-
dc.identifier.doi10.1177/15593258211052420-
dc.identifier.scopus85120488201-
local.contributor.employeePanov, V., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation, Institute of Industrial Ecology, The Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation; Bushueva, T., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Minigalieva, I., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Naumova, A., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Shur, V., School of Natural Sciences and Mathematics, The Ural Federal University, Ekaterinburg, Russian Federation; Shishkina, E., School of Natural Sciences and Mathematics, The Ural Federal University, Ekaterinburg, Russian Federation; Sutunkova, M., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Gurviсh, V., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Privalova, L., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Katsnelson, B., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federationen
local.issue4-
local.volume19-
dc.identifier.wos000726751500001-
local.contributor.departmentMedical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russian Federation; Institute of Industrial Ecology, The Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation; School of Natural Sciences and Mathematics, The Ural Federal University, Ekaterinburg, Russian Federationen
local.identifier.pure29066484-
local.identifier.eid2-s2.0-85120488201-
local.identifier.wosWOS:000726751500001-
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