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Title: Synthesis and Antifungal Activity of Diamidomethane Linked Oxazolyl/thiazolyl/imidazolyl Isoxazoles
Authors: Jyothi, S.
Madhusekhar, M.
Sravya, G.
Zyryanov, G. V.
Padmaja, A.
Issue Date: 2022
Publisher: American Institute of Physics Inc.
AIP Publishing
Citation: Synthesis and Antifungal Activity of Diamidomethane Linked Oxazolyl/thiazolyl/imidazolyl Isoxazoles / S. Jyothi, M. Madhusekhar, G. Sravya et al. // AIP Conference Proceedings. — 2022. — Vol. 2390. — 020024.
Abstract: Nitrogen containing heterocyclic compounds have great utility in synthetic, medicinal and material chemistry. Oxazole, isoxazole, thiazole, imidazole and their derivatives have gained prominence as they constitute the structural features of many bioactive compounds. In fact, amide functionality represents a privileged scaffold of biomolecules and many drugs. The combination of two or more heterocycles linked by amide functionality into one molecular framework would yield new chemical entities with enhanced pharmacological activities. Besides, development of environmentally benign methods with improved yields is highly desirable. In our continued interest to synthesize a variety of bioactive heterocycles, we planned to develop some new isoxazoles in combination with oxazoles / thiazoles / imidazoles adopting green methodologies and to study their antifungal activity. The results related to these aspects will be presented. © 2022 Author(s).
Access: info:eu-repo/semantics/openAccess
Conference name: 2020 International Scientific Conference on Actual Problems of Organic Chemistry and Biotechnology, OCBT 2020
Conference date: 18 November 2020 through 21 November 2020
SCOPUS ID: 85125666770
ISSN: 0094-243X
ISBN: 9780735441712
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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