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http://elar.urfu.ru/handle/10995/111599
Название: | Algorithms for Optimization of the Transport System in Living and Artificial Cells |
Авторы: | Melkikh, A. V. Sutormina, M. I. |
Дата публикации: | 2011 |
Издатель: | Springer Science and Business Media LLC |
Библиографическое описание: | Melkikh A. V. Algorithms for Optimization of the Transport System in Living and Artificial Cells / A. V. Melkikh, M. I. Sutormina // Systems and Synthetic Biology. — 2011. — Vol. 5. — Iss. 1. — P. 87-96. |
Аннотация: | An optimization of the transport system in a cell has been considered from the viewpoint of the operations research. Algorithms for an optimization of the transport system of a cell in terms of both the efficiency and a weak sensitivity of a cell to environmental changes have been proposed. The switching of various systems of transport is considered as the mechanism of weak sensitivity of a cell to changes in environment. The use of the algorithms for an optimization of a cardiac cell has been considered by way of example. We received theoretically for a cell of a cardiac muscle that at the increase of potassium concentration in the environment switching of transport systems for this ion takes place. This conclusion qualitatively coincides with experiments. The problem of synthesizing an optimal system in an artificial cell has been stated. © 2011 Springer Science+Business Media B.V. |
Ключевые слова: | EFFICIENCY GAME THEORY ROBUSTNESS SYNTHETIC BIOLOGY SYSTEMS BIOLOGY TRANSPORT OF IONS |
URI: | http://elar.urfu.ru/handle/10995/111599 |
Условия доступа: | info:eu-repo/semantics/openAccess |
Идентификатор SCOPUS: | 80052031531 |
Идентификатор PURE: | 30076914 |
ISSN: | 1872-5325 |
Располагается в коллекциях: | Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC |
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Файл | Описание | Размер | Формат | |
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2-s2.0-80052031531.pdf | 511,67 kB | Adobe PDF | Просмотреть/Открыть |
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