Микробные тест-системы как метод оценки влияния растительных биосубстратов на чувствительность бактерий Escherichia coli к антибиотикам

Abstract

Susceptibility of Escherichia coli to antibiotics was estimated by determination of the minimum inhibitory concentrations (MICs). To evalu-ate gene expression we measured в-galactosidase activity in strains carrying gene fusions using plate reader. It has been shown that treatment with polyphe-nols and some plant extracts significantly decreased bacteriostatic effects of antibiotics, to a larger extent, ciprofloxacin. A positive correlation was found among protective effects of polyphenols and extracts and their antioxidant properties.