Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/103223
Title: Influence of biopsy cores number performed with targeted prostate biopsy on the likelihood of a positive result in patients with clinically significant prostate cancer
Влияние количества биоптатов, взятых при таргетной биопсии предстательной железы, на вероятность положительного результата у пациентов с клинически значимым раком предстательной железы
Authors: Zyryanov, A. V.
Gulin, G. A.
Rubtsova, N. A.
Mager, V. O.
Putintsev, A. E.
Kuznetsova, S. G.
Kuznetsova, D. D.
Issue Date: 2020
Publisher: ABC-press Publishing House
Citation: Influence of biopsy cores number performed with targeted prostate biopsy on the likelihood of a positive result in patients with clinically significant prostate cancer / A. V. Zyryanov, G. A. Gulin, N. A. Rubtsova, et al. — DOI 10.17650/1726-9776-2020-16-3-62-69 // Onkourologiya. — 2020. — Vol. 16. — Iss. 3. — P. 62-69.
Abstract: Background. Targeted biopsy is proposed as a method of choice in the algorithm of prostate cancer diagnosis, but not all the features of method has been evaluated. Objective: determine the rational number of targeted biopsy samples in patients with clinically significant prostate cancer. Materials and methods. The magnetic resonance imaging and fusion biopsy data of 156 patients with suspected prostate cancer were retrospectively evaluated. Results and conclusion. In the study statistically significant dependence of the positive histological results in patients with clinically significant prostate cancer from the number of biopsy samples was found. The potential probability of a false negative histological examination with an insufficient number of biopsy samples was noted. These results confirm the latest published data of potential targeted biopsy false in true positive patients after multiparametric magnetic resonance imaging. An increase in the number of biopsy samples in the target lesion reduces the likelihood of false-negative results. The main causes of such discrepancy are some technical laxity and the heterogeneous histological structure of prostate cancer. Increase the number of biopsy cores can reduce the likelihood of false-negative results. © 2020 ABC-press Publishing House. All rights reserved.
Keywords: MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING
PROSTATE CANCER
TARGETED BIOPSY
ARTICLE
CANCER PATIENT
FALSE NEGATIVE RESULT
HISTOPATHOLOGY
HUMAN
HUMAN TISSUE
MAJOR CLINICAL STUDY
MALE
MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING
PROBABILITY
PROSTATE BIOPSY
PROSTATE CANCER
RETROSPECTIVE STUDY
STATISTICALLY SIGNIFICANT RESULT
URI: http://hdl.handle.net/10995/103223
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85097740042
PURE ID: 20242804
ISSN: 17269776
DOI: 10.17650/1726-9776-2020-16-3-62-69
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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