Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/103143
Title: C(sp2)-H functionalization in non-aromatic azomethine-based heterocycles
Authors: Akulov, A. A.
Varaksin, M. V.
Mampuys, P.
Charushin, V. N.
Chupakhin, O. N.
Maes, B. U. W.
Issue Date: 2021
Publisher: Royal Society of Chemistry
Citation: C(sp2)-H functionalization in non-aromatic azomethine-based heterocycles / A. A. Akulov, M. V. Varaksin, P. Mampuys, et al. — DOI 10.1039/d0ob01580f // Organic and Biomolecular Chemistry. — 2021. — Vol. 19. — Iss. 2. — P. 297-312.
Abstract: Direct C(sp2)-H functionalization of the endocyclic azomethine and aldonitrone moieties in non-aromatic azaheterocycles has established itself as a promising methodology over the last decade. Transition metal-catalyzed cross-coupling reactions, α-metalation-electrophile quenching protocols, and (metal-free) nucleophilic substitution of hydrogen reactions (SNH) are the major routes applied on cyclic imines and their derivatives. In this overview, we show the tangible progress made in this area during the period from 2008 to 2020. This journal is © The Royal Society of Chemistry.
Keywords: TRANSITION METALS
AZA-HETEROCYCLES
CYCLIC IMINES
ELECTROPHILES
FUNCTIONALIZATIONS
HETEROCYCLES
HYDROGEN REACTION
METAL-CATALYZED CROSS-COUPLING REACTIONS
NUCLEOPHILIC SUBSTITUTIONS
CHEMICAL REACTIONS
REVIEW
URI: http://hdl.handle.net/10995/103143
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85099739487
PURE ID: 20893290
d7457d3c-445b-4e42-a856-cd03ef42620b
ISSN: 14770520
DOI: 10.1039/d0ob01580f
metadata.dc.description.sponsorship: The research was financially supported by the Russian Science Foundation (Project No. 20-43-01004), a bilateral Russian Science Foundation (RSF) – Fund for Scientific Research Flanders (FWO) project, and the Francqui Foundation.
RSCF project card: 20-43-01004
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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