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|Title:||Engineering of a biomimetic interface between a native dental tissue and restorative composite and its study using synchrotron ftir microscopic mapping|
|Citation:||Engineering of a biomimetic interface between a native dental tissue and restorative composite and its study using synchrotron ftir microscopic mapping / P. Seredin, D. Goloshchapov, Y. Ippolitov, et al. — DOI 10.3390/ijms22126510 // International Journal of Molecular Sciences. — 2021. — Vol. 22. — Iss. 12. — 6510.|
|Abstract:||The aim of this work is to develop a biomimetic interface between the natural tooth tissue and the restorative composite and to study it on the basis of synchrotron micro-FTIR mapping and multidimensional processing of the spectral data array. Using hierarchical cluster analysis of 3D FTIR data revealed marked improvements in the formation of the dentine/adhesive/dental hybrid interface using a biomimetic approach. The use of a biomimetic strategy (application of an amino acid– modified primer, alkaline calcium and a nano-c-HAp–modified adhesive) allowed the formation of a matrix that can be structurally integrated with natural dentine and dental composite. The biomimetic hybrid layer was characterised by homogeneous chemical composition and a higher degree of conversion of the adhesive during polymerisation, which should provide optimal integration of the dental composite with the dentine. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.|
|metadata.dc.description.sponsorship:||This work was supported by the grant of Russian Science Foundation, grant number 21-15-00026.|
|RSCF project card:||21-15-00026|
|Appears in Collections:||Научные публикации, проиндексированные в SCOPUS и WoS CC|
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