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dc.contributor.authorLopez-Lopez, M. T.en
dc.contributor.authorRodriguez, I. A.en
dc.contributor.authorRodriguez-Arco, L.en
dc.contributor.authorCarriel, V.en
dc.contributor.authorBonhome-Espinosa, A. B.en
dc.contributor.authorCampos, F.en
dc.contributor.authorZubarev, A.en
dc.contributor.authorDuran, J. D. G.en
dc.date.accessioned2021-08-31T15:02:03Z-
dc.date.available2021-08-31T15:02:03Z-
dc.date.issued2017-
dc.identifier.citationSynthesis, characterization and in vivo evaluation of biocompatible ferrogels / M. T. Lopez-Lopez, I. A. Rodriguez, L. Rodriguez-Arco, et al. — DOI 10.1016/j.jmmm.2016.08.053 // Journal of Magnetism and Magnetic Materials. — 2017. — Vol. 431. — P. 110-114.en
dc.identifier.issn3048853-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Green3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85015737352&doi=10.1016%2fj.jmmm.2016.08.053&partnerID=40&md5=468b7516e7edfb30667410c806cc20ee
dc.identifier.otherhttps://digibug.ugr.es/bitstream/10481/67730/1/MAGMA%2061738.pdfm
dc.identifier.urihttp://elar.urfu.ru/handle/10995/102140-
dc.description.abstractA hydrogel is a 3-D network of polymer chains in which water is the dispersion medium. Hydrogels have found extensive applications in the biomedical field due to their resemblance to living tissues. Furthermore, hydrogels can be endowed with exceptional properties by addition of synthetic materials. For example, magnetic field-sensitive gels, called ferrogels, are obtained by embedding magnetic particles in the polymer network. Novel living tissues with unique magnetic field-sensitive properties were recently prepared by 3-D cell culture in biocompatible ferrogels. This paper critically reviews the most recent progress and perspectives in their synthesis, characterization and biocompatibility evaluation. Optimization of ferrogels for this novel application requires low-density, strongly magnetic, multi-domain particles. Interestingly, the rheological properties of the resulting ferrogels in the absence of field were largely enhanced with respect to nonmagnetic hydrogels, which can only be explained by the additional cross-linking imparted by the embedded magnetic particles. Remarkably, rheological measurements under an applied magnetic field demonstrated that ferrogels presented reversibly tunable mechanical properties, which constitutes a unique advantage with respect to nonmagnetic hydrogels. In vivo evaluation of ferrogels showed good biocompatibility, with only some local inflammatory response, and no particle migration or damage to distant organs. © 2016 Elsevier B.V.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherElsevier B.V.en
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceJ Magn Magn Mater2
dc.sourceJournal of Magnetism and Magnetic Materialsen
dc.subjectFERROGELen
dc.subjectIN VIVOen
dc.subjectMAGNETIC PARTICLEen
dc.subjectMAGNETORHEOLOGYen
dc.subjectPOLYMERen
dc.subjectRHEOLOGYen
dc.subjectBIOCOMPATIBILITYen
dc.subjectBIOMECHANICSen
dc.subjectCELL CULTUREen
dc.subjectHISTOLOGYen
dc.subjectHYDROGELSen
dc.subjectMAGNETIC FIELDSen
dc.subjectMAGNETISMen
dc.subjectPOLYMERSen
dc.subjectRHEOLOGYen
dc.subjectTISSUEen
dc.subjectAPPLIED MAGNETIC FIELDSen
dc.subjectFERROGELen
dc.subjectIN-VIVOen
dc.subjectINFLAMMATORY RESPONSEen
dc.subjectMAGNETIC PARTICLEen
dc.subjectMAGNETO-RHEOLOGYen
dc.subjectRHEOLOGICAL MEASUREMENTSen
dc.subjectRHEOLOGICAL PROPERTYen
dc.subjectMAGNETIC BUBBLESen
dc.titleSynthesis, characterization and in vivo evaluation of biocompatible ferrogelsen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1016/j.jmmm.2016.08.053-
dc.identifier.scopus85015737352-
local.contributor.employeeLopez-Lopez, M.T., Department of Applied Physics, University of Granada, Granada, Spain, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
local.contributor.employeeRodriguez, I.A., Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain, Department of Histology (Tissue Engineering Group), University of Granada, Granada, Spain
local.contributor.employeeRodriguez-Arco, L., Department of Applied Physics, University of Granada, Granada, Spain, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
local.contributor.employeeCarriel, V., Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain, Department of Histology (Tissue Engineering Group), University of Granada, Granada, Spain
local.contributor.employeeBonhome-Espinosa, A.B., Department of Applied Physics, University of Granada, Granada, Spain, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
local.contributor.employeeCampos, F., Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain, Department of Histology (Tissue Engineering Group), University of Granada, Granada, Spain
local.contributor.employeeZubarev, A., Department of Mathematical Physics, Ural Federal University, Ekaterinburg, Russian Federation
local.contributor.employeeDuran, J.D.G., Department of Applied Physics, University of Granada, Granada, Spain, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
local.description.firstpage110-
local.description.lastpage114-
local.volume431-
local.contributor.departmentDepartment of Applied Physics, University of Granada, Granada, Spain
local.contributor.departmentInstituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
local.contributor.departmentDepartment of Histology (Tissue Engineering Group), University of Granada, Granada, Spain
local.contributor.departmentDepartment of Mathematical Physics, Ural Federal University, Ekaterinburg, Russian Federation
local.identifier.pure1691284-
local.identifier.purefacf6479-07df-478f-8cfe-cd802789ecd1uuid
local.identifier.eid2-s2.0-85015737352-
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