Please use this identifier to cite or link to this item:
https://elar.urfu.ru/handle/10995/101864
Title: | Synthesis, spectroscopic characterization and molecular docking studies of 2-butyl-4-chloro-5-formylimidazole thiosemicarbazone cobalt(II) complex |
Authors: | Reddy, A. S. Krishna, L. S. Badavath, V. N. Sravya, G. Reddy, N. B. Zyryanov, G. V. Зырянов, Г. В. |
Issue Date: | 2019 |
Publisher: | American Institute of Physics Inc. |
Citation: | Synthesis, spectroscopic characterization and molecular docking studies of 2-butyl-4-chloro-5-formylimidazole thiosemicarbazone cobalt(II) complex / A. S. Reddy, L. S. Krishna, V. N. Badavath, et al. — DOI 10.1063/1.5087386 // AIP Conference Proceedings. — 2019. — Vol. 2063. — 040054. |
Abstract: | A novel 2-Butyl-4-chloro-5-formylimidazole thiosemicarbazonecobalt (II) complex is synthesized and characterized by using spectroscopic techniques like elemental analysis, FT-IR, HRMS, electronic spectral analysis and Powder-X-ray diffraction. The Co(II) complex is found to be highly efficient in inhibiting the growth of human pathogens likeS. aureusand B. megaterium with MIC value 12.0 μg/mL whose inhibition zones are almost comparable with the standard antibiotic. The synthesized complex well occupies in the active site of β- ketoacyl-acyl carrier protein synthase III enzyme (PDB: 1MZS), in consists of catalytic triad and adenine-binding site, so the designed compoundis promising for to treat bacterial infection. © 2019 Author(s). |
URI: | http://elar.urfu.ru/handle/10995/101864 |
Access: | info:eu-repo/semantics/openAccess |
SCOPUS ID: | 85060432122 |
WOS ID: | 000598565200079 |
PURE ID: | 11def740-74dc-46a3-a8e6-ab4c7b095959 8870317 |
ISSN: | 0094243X |
ISBN: | 9780735417915 |
DOI: | 10.1063/1.5087386 |
Appears in Collections: | Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC |
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