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Title: Synthesis and antimicrobial activity of spiroheterocycles
Authors: Teja, G. L.
Sankar, P. S.
Reddy, N. B.
Padmavathi, V.
Zyryanov, G. V.
Зырянов, Г. В.
Issue Date: 2019
Publisher: American Institute of Physics Inc.
Citation: Synthesis and antimicrobial activity of spiroheterocycles / G. L. Teja, P. S. Sankar, N. B. Reddy, et al. — DOI 10.1063/1.5087391 // AIP Conference Proceedings. — 2019. — Vol. 2063. — 040059.
Abstract: A new class of spiroheterocycles-pyrazolinyl thienofuranones and isoxazolinyl thienofuranones were prepared from benzylidene thienofuranones by 1,3-dipolar cycloaddition of nitrile imines and nitrile oxides. The dipolar reagents were generated from araldehyde phenylhydrazones and araldoximes in the presence of phase transfer catalyst. All the compounds are tested for their antimicrobial activity. Chloro substituted pyrazolinyl and isoxazolinyl thienofuranones displayed prominent antibacterial activity against B. subtilis greater than the standard drug Chloramphenicol and antifungal activity against A. niger greater than Ketoconazole. © 2019 Author(s).
Access: info:eu-repo/semantics/openAccess
SCOPUS ID: 85060477790
PURE ID: 8867853
ISSN: 0094243X
ISBN: 9780735417915
DOI: 10.1063/1.5087391
Appears in Collections:Научные публикации, проиндексированные в SCOPUS и WoS CC

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