Разработка новых потенциальных флуоресцентных маркеров ДНК

Abstract

Nucleic acid electrophoresis is an analytical technique used to separate DNA fragments by size and reactivity. The electrophoresis results are registered in the sense of ethidium bromide which is considered to be carcinogenic and teratogenic. The number of new potential fluorescent DNA stains were developed due to the novel approach to the [1,2,4]triazolo[1,5-a]pyrimidine nucleophilic functionalization.