Targeted drug delivery system based on manganese-doped mesoporous silica nanopowder

Abstract

The purpose of the research was to investigate the potential of using SiO2-MnO2 nanopowder, obtained by electron beam evaporation, as a drug delivery system. The evaluation of the sedimentation stability of suspensions was conducted for further in vivo studies. It was established that PEG stabilized suspensions showed the highest stability. Drug loading and release experiments with nanopowders demonstrated a high drug loading capacity of Amoxicillin and Doxorubicin.