Метод карбоновых волокон для измерения сократительных свойств изолированных кардиомиоцитов

Abstract

The direct mechanical measurement of the contractility of an isolated cardiac cell can be realized by the method of carbon fibers (CF). In this method, two CFs are attached to the cell. If weakly attached, CFs may slip out of cell surface under stretch of a cell. This resulted in the deficiency of sarcomere stretch as compared to cell stretch. The purpose of this study was to evaluate the imbalance between the cell and sarcomere stretch in isolated ventricular cardiomyocytes.