Please use this identifier to cite or link to this item: http://hdl.handle.net/10995/102650
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dc.contributor.authorSutunkova, M. P.en
dc.contributor.authorMinigalieva, I. A.en
dc.contributor.authorPanov, V. G.en
dc.contributor.authorRiabova, Iu. V.en
dc.contributor.authorShur, V. Ya.en
dc.contributor.authorZubarev, I. V.en
dc.contributor.authorShishkina, E. V.en
dc.contributor.authorPrivalova, L. I.en
dc.contributor.authorKatsnelson, B. A.en
dc.contributor.authorШур, В. Я.ru
dc.date.accessioned2021-08-31T15:04:34Z-
dc.date.available2021-08-31T15:04:34Z-
dc.date.issued2020-
dc.identifier.citationMultisystemic damage to mitochondrial ultrastucture as an integral measure of the comparative in vivo cytotoxicity of metallic nanoparticles / M. P. Sutunkova, I. A. Minigalieva, V. G. Panov, et al. — DOI 10.1088/1757-899X/918/1/012119 // IOP Conference Series: Materials Science and Engineering. — 2020. — Vol. 918. — Iss. 1. — 012119.en
dc.identifier.issn17578981-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access, Bronze3
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85094176752&doi=10.1088%2f1757-899X%2f918%2f1%2f012119&partnerID=40&md5=e8a877ad6b1a3fffba4421649a78ca92
dc.identifier.urihttp://hdl.handle.net/10995/102650-
dc.description.abstractVehicles emissions of nanoparticles is a one of the major threat to humans in the modern conditions. Subchronic intoxication was induced in outbred male rats by repeated intraperitoneal injections of lead oxide, zinc oxide and copper oxide nanoparticles separately, or in three binary combinations, or in the full triple combination. Based on electron microscopy results, this paper considers the usefulness, feasibility and informativity of an approach based on a generalized semi-quantitative assessment of toxic damage to mitochondria in various organs using partial or complete destruction of cristae as an index of damage. The adequacy of such assessment is confirmed by its consistency with the previously published data on the relative and combined toxicity of nanoparticles of the above species and high protective efficacy of a complex of bioprotectors estimated by a great number of functional and optical-microscopy morphometric indices. © Published under licence by IOP Publishing Ltd.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherIOP Publishing Ltden
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.sourceIOP Conf. Ser. Mater. Sci. Eng.2
dc.sourceIOP Conference Series: Materials Science and Engineeringen
dc.titleMultisystemic damage to mitochondrial ultrastucture as an integral measure of the comparative in vivo cytotoxicity of metallic nanoparticlesen
dc.typeConference Paperen
dc.typeinfo:eu-repo/semantics/conferenceObjecten
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1088/1757-899X/918/1/012119-
dc.identifier.scopus85094176752-
local.contributor.employeeSutunkova, M.P., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.employeeMinigalieva, I.A., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.employeePanov, V.G., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.employeeRiabova, Iu.V., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.employeeShur, V.Ya., School of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation
local.contributor.employeeZubarev, I.V., School of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation
local.contributor.employeeShishkina, E.V., School of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation
local.contributor.employeePrivalova, L.I., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.employeeKatsnelson, B.A., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.issue1-
local.volume918-
local.contributor.departmentMedical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russian Federation
local.contributor.departmentSchool of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation
local.identifier.pure20129960-
local.identifier.pure613749e7-cf52-4e39-9158-0e6780b7d123uuid
local.description.order012119-
local.identifier.eid2-s2.0-85094176752-
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