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Полная запись метаданных
Поле DC | Значение | Язык |
---|---|---|
dc.contributor.author | Khan, K. M. | en |
dc.contributor.author | Collier, A. D. | en |
dc.contributor.author | Meshalkina, D. A. | en |
dc.contributor.author | Kysil, E. V. | en |
dc.contributor.author | Khatsko, S. L. | en |
dc.contributor.author | Kolesnikova, T. | en |
dc.contributor.author | Morzherin, Y. Y. | en |
dc.contributor.author | Warnick, J. E. | en |
dc.contributor.author | Kalueff, A. V. | en |
dc.contributor.author | Echevarria, D. J. | en |
dc.date.accessioned | 2019-07-22T06:43:56Z | - |
dc.date.available | 2019-07-22T06:43:56Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | Zebrafish models in neuropsychopharmacology and CNS drug discovery / K. M. Khan, A. D. Collier, D. A. Meshalkina et al. // British Journal of Pharmacology. — 2017. — Vol. 174. — Iss. 13. — P. 1925-1944. | en |
dc.identifier.issn | 0007-1188 | - |
dc.identifier.other | https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.13754 | |
dc.identifier.other | 1 | good_DOI |
dc.identifier.other | d2b6dbb2-042a-4b69-a525-d80728cdf0c7 | pure_uuid |
dc.identifier.other | http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85017091455 | m |
dc.identifier.uri | http://elar.urfu.ru/handle/10995/75103 | - |
dc.description.abstract | Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized as a powerful animal model in neuropharmacology research and in vivo drug screening. Collectively, this makes zebrafish a useful tool for drug discovery and the identification of disordered molecular pathways. Here, we discuss zebrafish models of selected human neuropsychiatric disorders and drug-induced phenotypes. As well as covering a broad range of brain disorders (from anxiety and psychoses to neurodegeneration), we also summarize recent developments in zebrafish genetics and small molecule screening, which markedly enhance the disease modelling and the discovery of novel drug targets. © 2017 The British Pharmacological Society | en |
dc.description.sponsorship | The study was coordinated through the International Zebrafish Neuroscience Research Consortium (ZNRC), and this collaboration was funded by St. Petersburg State University, Ural Federal University and Guangdong Ocean University. A.V.K. is the Chair of ZNRC, and his research is supported by the Russian Foundation for Basic Research (RFBR) grant 16-04-00851. | en |
dc.format.mimetype | application/pdf | en |
dc.language.iso | en | en |
dc.publisher | John Wiley and Sons Inc. | en |
dc.rights | info:eu-repo/semantics/openAccess | en |
dc.source | British Journal of Pharmacology | en |
dc.subject | ALCOHOL | en |
dc.subject | AMPHETAMINE DERIVATIVE | en |
dc.subject | ANTICONVULSIVE AGENT | en |
dc.subject | COCAINE | en |
dc.subject | NEUROLEPTIC AGENT | en |
dc.subject | NICOTINE | en |
dc.subject | PSYCHEDELIC AGENT | en |
dc.subject | SEDATIVE AGENT | en |
dc.subject | CENTRAL NERVOUS SYSTEM AGENTS | en |
dc.subject | ALZHEIMER DISEASE | en |
dc.subject | AMYOTROPHIC LATERAL SCLEROSIS | en |
dc.subject | ANIMAL MODEL | en |
dc.subject | ANXIETY DISORDER | en |
dc.subject | AUTOMATION | en |
dc.subject | CENTRAL NERVOUS SYSTEM | en |
dc.subject | DEPRESSION | en |
dc.subject | DRUG ABUSE | en |
dc.subject | DRUG SCREENING | en |
dc.subject | DRUG SENSITIVITY | en |
dc.subject | DRUG TARGETING | en |
dc.subject | EPILEPSY | en |
dc.subject | GENETIC MODEL | en |
dc.subject | GENETIC SCREENING | en |
dc.subject | HIGH THROUGHPUT SCREENING | en |
dc.subject | NERVE DEGENERATION | en |
dc.subject | NONHUMAN | en |
dc.subject | PRIORITY JOURNAL | en |
dc.subject | PSYCHOPHARMACOLOGY | en |
dc.subject | PSYCHOSIS | en |
dc.subject | REVIEW | en |
dc.subject | ZEBRA FISH | en |
dc.subject | ANIMAL | en |
dc.subject | CENTRAL NERVOUS SYSTEM DISEASE | en |
dc.subject | CHEMISTRY | en |
dc.subject | DISEASE MODEL | en |
dc.subject | DRUG DEVELOPMENT | en |
dc.subject | MOLECULAR LIBRARY | en |
dc.subject | PRECLINICAL STUDY | en |
dc.subject | SYNTHESIS | en |
dc.subject | THERAPEUTIC USE | en |
dc.subject | ZEBRA FISH | en |
dc.subject | ANIMALS | en |
dc.subject | CENTRAL NERVOUS SYSTEM AGENTS | en |
dc.subject | CENTRAL NERVOUS SYSTEM DISEASES | en |
dc.subject | DISEASE MODELS, ANIMAL | en |
dc.subject | DRUG DISCOVERY | en |
dc.subject | DRUG EVALUATION, PRECLINICAL | en |
dc.subject | SMALL MOLECULE LIBRARIES | en |
dc.subject | ZEBRAFISH | en |
dc.title | Zebrafish models in neuropsychopharmacology and CNS drug discovery | en |
dc.type | Review | en |
dc.type | info:eu-repo/semantics/review | en |
dc.type | info:eu-repo/semantics/publishedVersion | en |
dc.identifier.doi | 10.1111/bph.13754 | - |
dc.identifier.scopus | 85017091455 | - |
local.affiliation | Department of Psychology, University of Southern Mississippi, Hattiesburg, MS, United States | en |
local.affiliation | The International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, LA, United States | en |
local.affiliation | Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russian Federation | en |
local.affiliation | Ural Federal University, Ekaterinburg, Russian Federation | en |
local.affiliation | Department of Behavioral Sciences, Arkansas Tech University, Russellville, AR, United States | en |
local.affiliation | Research Institute of Marine Drugs and Nutrition, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, Guangdong, China | en |
local.contributor.employee | Хацко Сергей Леонидович | ru |
local.contributor.employee | Колесникова Татьяна Олеговна | ru |
local.contributor.employee | Моржерин Юрий Юрьевич | ru |
local.contributor.employee | Калуев Алан Валерьевич | ru |
local.description.firstpage | 1925 | - |
local.description.lastpage | 1944 | - |
local.issue | 13 | - |
local.volume | 174 | - |
dc.identifier.wos | 000403299900005 | - |
local.identifier.pure | 1924696 | - |
local.identifier.eid | 2-s2.0-85017091455 | - |
local.identifier.wos | WOS:000403299900005 | - |
Располагается в коллекциях: | Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC |
Файлы этого ресурса:
Файл | Описание | Размер | Формат | |
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10.1111-bph.13754.pdf | 1,2 MB | Adobe PDF | Просмотреть/Открыть |
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