1. Электронный научный архив УрФУ
  2. 00. Общеуниверситетские коллекции
  3. Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC
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dc.contributor.authorElmas, O.en
dc.contributor.authorSahin, H. H. K.en
dc.contributor.authorGuven, B.en
dc.contributor.authorAbuzaid, M. M.en
dc.contributor.authorElshami, W.en
dc.contributor.authorAlmisned, G.en
dc.contributor.authorZakaly, H. M. H.en
dc.contributor.authorEne, A.en
dc.contributor.authorTekin, H. O.en
dc.date.accessioned2024-04-08T11:06:57Z-
dc.date.available2024-04-08T11:06:57Z-
dc.date.issued2022-
dc.identifier.citationElmas, O, Sahin, HHK, Guven, B, Abuzaid, MM, Elshami, W, Almisned, G, Zakaly, HMH, Ene, A & Tekin, HO 2022, 'A focusing study on radioprotective and antioxidant effects of Annona muricata leaf extract in the circulation and liver tissue: Clinical and experimental studies', Open chemistry, Том. 20, № 1, стр. 920-928. https://doi.org/10.1515/chem-2022-0206harvard_pure
dc.identifier.citationElmas, O., Sahin, H. H. K., Guven, B., Abuzaid, M. M., Elshami, W., Almisned, G., Zakaly, H. M. H., Ene, A., & Tekin, H. O. (2022). A focusing study on radioprotective and antioxidant effects of Annona muricata leaf extract in the circulation and liver tissue: Clinical and experimental studies. Open chemistry, 20(1), 920-928. https://doi.org/10.1515/chem-2022-0206apa_pure
dc.identifier.issn2391-5420-
dc.identifier.otherFinal2
dc.identifier.otherAll Open Access; Gold Open Access3
dc.identifier.otherhttps://www.degruyter.com/document/doi/10.1515/chem-2022-0206/pdf1
dc.identifier.otherhttps://www.degruyter.com/document/doi/10.1515/chem-2022-0206/pdfpdf
dc.identifier.urihttp://elar.urfu.ru/handle/10995/131374-
dc.description.abstractObjectives: This study investigates the effect of Annona muricata (AM) leaf extract against irradiation-induced damage by the evaluation of hepatic tissue and the levels of oxidative and inflammatory stress in the circulation. Methods: An experimental study with 37 female Wistar albino rats randomized into four groups (controls and three intervention groups) was performed. The first interventional group (group 2) received 300 mg/kg of AM leaf extract by oral gavage once a day for 9 days, group 3 received a single dose of whole-body radiation (8.3 Gy) after a 9-day oral gavage treatment with saline, and the last group received the same irradiation of 8.3 Gy after being treated with 300 mg/kg of AM leaf extract by oral gavage once a day for 9 days. Results: Radiation was found to elevate reactive oxygen species parameters, and AM administration before irradiation was found to decrease total oxidant status (TOS), increase caspase 9, and improve hepatic damage when compared with the group that received only irradiation. Conclusion: The damage caused by irradiation may be ameliorated by the use of the AM extract, which appears to be effective in preventing oxidative stress and inflammatory activity. © 2022 Ozlem Elmas et al.en
dc.description.sponsorshipDunarea de Jos” University of Galatien
dc.description.sponsorshipUniversitatea 'Dunărea de Jos' Galați, UDJG, (RF 3621/2021)en
dc.description.sponsorshipFunding text 1: Author contributions: O.E., H.H.K.S., H.O.T.: conceptualization and methodologyen
dc.description.sponsorshipM.A., W.E., G.A.: validationen
dc.description.sponsorshipG.A. and H.M.H.Z.: formal analysisen
dc.description.sponsorshipO.E., H.H.K.S., B.G., H.O.T.: writing and reviewen
dc.description.sponsorshipO.E., H.H.K.S., B.G., A.E., M.A., W.E.: investigationen
dc.description.sponsorshipA.E.: funding acquisition through APC by “Dunarea de Jos” University of Galati, Romania through the grant no. RF 3621/2021.en
dc.description.sponsorshipFunding text 2: Funding information: The work of Antoaneta ENE and the APC were supported by Dunarea de Jos University of Galati, Romania through the grant no. RF 3621/2021.en
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherDe Gruyter Open Ltden
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.rightscc-byother
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/unpaywall
dc.sourceOpen Chemistry2
dc.sourceOpen Chemistryen
dc.subjectANNONA MURICATAen
dc.subjectAPOPTOSISen
dc.subjectIRRADIATIONen
dc.subjectOXIDATIVE STRESSen
dc.subjectRADIOPROTECTIVEen
dc.titleA focusing study on radioprotective and antioxidant effects of Annona muricata leaf extract in the circulation and liver tissue: Clinical and experimental studiesen
dc.typeArticleen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeinfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1515/chem-2022-0206-
dc.identifier.scopus85139254835-
local.contributor.employeeElmas O., Department of Radiation Oncology, Bulent Ecevit University Practice and Research Hospital, Zonguldak, Turkeyen
local.contributor.employeeSahin H.H.K., Department of Pathology, Hitit University Corum Training and Research Hospital, Corum, Turkeyen
local.contributor.employeeGuven B., Department of Biochemistry, Bulent Ecevit University Practice and Research Hospital, Zonguldak, Turkeyen
local.contributor.employeeAbuzaid M.M., Department of Medical Diagnostic Imaging, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emiratesen
local.contributor.employeeElshami W., Department of Medical Diagnostic Imaging, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emiratesen
local.contributor.employeeAlmisned G., Department of Physics, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabiaen
local.contributor.employeeZakaly H.M.H., Institute of Physics and Technology, Ural Federal University, Ekaterinburg, 620002, Russian Federation, Physics Department, Faculty of Science, Al-Azhar University, Assiut, 71524, Egypten
local.contributor.employeeEne A., Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, INPOLDE Research Center, Dunarea de Jos University of Galati, 47 Domneasca Street, Galati, 800008, Romaniaen
local.contributor.employeeTekin H.O., Department of Medical Diagnostic Imaging, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates, Computer Engineering Department, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul, 34396, Turkeyen
local.description.firstpage920-
local.description.lastpage928-
local.issue1-
local.volume20-
dc.identifier.wos000858430000001-
local.contributor.departmentDepartment of Radiation Oncology, Bulent Ecevit University Practice and Research Hospital, Zonguldak, Turkeyen
local.contributor.departmentDepartment of Pathology, Hitit University Corum Training and Research Hospital, Corum, Turkeyen
local.contributor.departmentDepartment of Biochemistry, Bulent Ecevit University Practice and Research Hospital, Zonguldak, Turkeyen
local.contributor.departmentDepartment of Medical Diagnostic Imaging, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emiratesen
local.contributor.departmentDepartment of Physics, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabiaen
local.contributor.departmentInstitute of Physics and Technology, Ural Federal University, Ekaterinburg, 620002, Russian Federationen
local.contributor.departmentPhysics Department, Faculty of Science, Al-Azhar University, Assiut, 71524, Egypten
local.contributor.departmentDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, INPOLDE Research Center, Dunarea de Jos University of Galati, 47 Domneasca Street, Galati, 800008, Romaniaen
local.contributor.departmentComputer Engineering Department, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul, 34396, Turkeyen
local.identifier.pure30946782-
local.identifier.purea6b1735e-322e-4d98-bc27-800da96d836fuuid
local.identifier.eid2-s2.0-85139254835-
local.identifier.wosWOS:000858430000001-
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