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http://elar.urfu.ru/handle/10995/117870
Название: | Electrochemical Aptasensors for Antibiotics Detection: Recent Achievements and Applications for Monitoring Food Safety |
Авторы: | Evtugyn, G. Porfireva, A. Tsekenis, G. Oravczova, V. Hianik, T. |
Дата публикации: | 2022 |
Издатель: | MDPI |
Библиографическое описание: | Electrochemical Aptasensors for Antibiotics Detection: Recent Achievements and Applications for Monitoring Food Safety / G. Evtugyn, A. Porfireva, G. Tsekenis et al. // Sensors. — 2022. — Vol. 22. — Iss. 10. — 3684. |
Аннотация: | Antibiotics are often used in human and veterinary medicine for the treatment of bacterial diseases. However, extensive use of antibiotics in agriculture can result in the contamination of common food staples such as milk. Consumption of contaminated products can cause serious illness and a rise in antibiotic resistance. Conventional methods of antibiotics detection such are microbiological assays chromatographic and mass spectroscopy methods are sensitive; however, they require qualified personnel, expensive instruments, and sample pretreatment. Biosensor technology can overcome these drawbacks. This review is focused on the recent achievements in the electrochemical biosensors based on nucleic acid aptamers for antibiotic detection. A brief explanation of conventional methods of antibiotic detection is also provided. The methods of the aptamer selection are explained, together with the approach used for the improvement of aptamer affinity by post-SELEX modification and computer modeling. The substantial focus of this review is on the explanation of the principles of the electrochemical detection of antibiotics by aptasensors and on recent achievements in the development of electrochemical aptasensors. The current trends and problems in practical applications of aptasensors are also discussed. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
Ключевые слова: | ANTIBIOTICS COMPUTER SIMULATIONS DNA APTAMERS ELECTROCHEMICAL SENSORS BIOSENSORS CHEMICAL DETECTION DISEASES ELECTROCHEMICAL SENSORS MASS SPECTROMETRY SPECTROSCOPIC ANALYSIS VETERINARY MEDICINE ANTIBIOTICS RESISTANCE APTAMERS APTASENSORS BACTERIAL DISEASE CONTAMINATED PRODUCT CONVENTIONAL METHODS DNA APTAMER ELECTROCHEMICAL APTASENSOR FOOD-SAFETY MONITORING FOODS ANTIBIOTICS ANTIINFECTIVE AGENT APTAMER CHEMISTRY CHROMATOGRAPHY FOOD SAFETY GENETIC PROCEDURES HUMAN PROCEDURES ANTI-BACTERIAL AGENTS APTAMERS, NUCLEOTIDE BIOSENSING TECHNIQUES CHROMATOGRAPHY FOOD SAFETY HUMANS |
URI: | http://elar.urfu.ru/handle/10995/117870 |
Условия доступа: | info:eu-repo/semantics/openAccess |
Идентификатор SCOPUS: | 85129810387 |
Идентификатор WOS: | 000803176000001 |
Идентификатор PURE: | 30208267 |
ISSN: | 14248220 |
DOI: | 10.3390/s22103684 |
Сведения о поддержке: | 1/0419/20; Horizon 2020 Framework Programme, H2020; H2020 Marie Skłodowska-Curie Actions, MSCA: 101007299; Kazan Federal University: PRIORITY-2030 Acknowledgments: G.E. acknowledges the support from the Kazan Federal University Strategic Academic Leadership Program (‘PRIORITY-2030’). Funding: T.H. acknowledges funding from the Science Grant Agency VEGA, project No.: 1/0419/20. This study was also funded under European Union’s Horizon 2020 research and innovation program through the Marie Skłodowska-Curie Grant Agreement No. 101007299. |
Располагается в коллекциях: | Научные публикации ученых УрФУ, проиндексированные в SCOPUS и WoS CC |
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Файл | Описание | Размер | Формат | |
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2-s2.0-85129810387.pdf | 2,64 MB | Adobe PDF | Просмотреть/Открыть |
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