Features of –C–C– Coupling of Quinoxaline-2-one with Ethyl Acetoacetate under Acid Catalysis

Abstract

Quinoxalin-2-one (1) reacts with ethyl acetoacetate in trifluoroacetic acid (TFA) to form 3-(2-oxopropylideno)-3,4-dihydroquinoxaline-2-one (2) and 3-(3-oxo-3,4- dihydroquinoxaline-2-(1H)-ylidene)methylquinoxaline-2-(1H)-one (3). The reaction product 3 was also obtained by heating the compound 1 with acetone in the presence of TFA.